Rabbit Anti-FKBP5 Recombinant Antibody (clone R08-8E5) (CAT#: VS3-FY1718)
This anti-FKBP51 antibody tested in western blot analysis of FKBP51 in CHO-K1 lysates. We develop this astounding rabbit recombinant monoclonal antibody that is direct against human and hamster FKBP5. It is suitable for use in a variety of assays, including WB, IP.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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WB
Figure 1 Anti-FKBP5 Antibody (VS3-FY1718) in WB.
The FKBP51 expression in CHO-K1 lysates were detected using the anti-FKBP51 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human FKBP51
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Hamster FKBP5
- Species Reactivity
- Human, Hamster
- Clone
- R08-8E5
- Applications
- Western Blot, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 51 kDa, while the observed molecular weight stands at 51 kDa.
- Related Disease
- Major Depressive Disorder and Asthma
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- FK506 Binding Protein 5; 54 KDa Progesterone Receptor-Associated Immunophilin; 51 KDa FK506-Binding Protein; Androgen-Regulated Protein 6; HSP90-Binding Immunophilin; FK506-Binding Protein 5; PPIase FKBP5; 51 KDa FKBP; FF1 Antigen; EC 5.2.1.8; Rotamase; FKBP-51
- Gene ID
- 2289
- UniProt ID
- Q13451
- Cellular Localization
- Chromosome, Nucleus
- Post Translation Modifications
- Acetylation impairs ability to promote interaction between Akt/AKT1 and PHLPP1 (PubMed:28147277).
Deacetylation by SIRT7 promotes interaction between Akt/AKT1 and PHLPP1, leading to suppress Akt/AKT1 activation (PubMed:28147277).
- Protein Refseq
- NP_001139247.1; NP_001139248.1; NP_001139249.1; NP_004108.1
- Function
- Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors maintaining the complex into the cytoplasm when unliganded.
Acts as a regulator of Akt/AKT1 activity by promoting the interaction between Akt/AKT1 and PHLPP1, thereby enhancing dephosphorylation and subsequent activation of Akt/AKT1.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1311 | Hi-Affi™ Rabbit Anti-FKBP5 Recombinant Antibody (clone DS1311AB) | WB, IHC, ICC, IP, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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