CytoStream™ Rabbit Anti-FLNA Recombinant Antibody (VS13-YC404) (CAT#: VS13-YC404)
The CytoStream™ Rabbit Anti-FLNA Recombinant Antibody is specific for human and mouse FLNA. FLNA encodes an actin-binding protein facilitating cytoskeletal remodeling, impacting cell migration pathways; defects cause syndromes like PVNH and various dysplasias due to its structural network roles. The anti-FLNA antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/368/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/368/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2925/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2925/if_selected.jpg
Figure 3 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/if_selected.jpg
Figure 4 Seminal vesicle
(High expression in seminal vesicle)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1115/2818_A_8_6_selected.jpg
(High expression in seminal vesicle)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1115/2818_A_8_6_selected.jpg
Figure 5 Cerebral cortex
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/2854_B_7_5.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/2854_B_7_5.jpg
Figure 6 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/2854_A_8_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/2854_A_8_4.jpg
Figure 7 Pancreas
(Exocrine glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/2854_A_3_3.jpg
(Exocrine glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/2854_A_3_3.jpg
Figure 8 Kidney
(Bowman's capsule Staining: High Intensity: Strong Quantity:>75% Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Collecting ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Distal tubules Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/2854_A_9_5.jpg
(Bowman's capsule Staining: High Intensity: Strong Quantity:>75% Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Collecting ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Distal tubules Staining: High Intensity: Strong Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/2854_A_9_5.jpg
Figure 9 Testis
(Peritubular cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/2854_A_6_6.jpg
(Peritubular cells Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/2854_A_6_6.jpg
Figure 10 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/2854_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/356/2854_A_8_8.jpg
Figure 11 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196924-FLNA
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196924-FLNA
Specifications
- Immunogen
- Recombinant human Filamin A, aa 2598-2647.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse FLNA
- Species Reactivity
- Human, Mouse
- Applications
- WB, ICC, IF, IHC-P, FC
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500
Immunocytochemistry (ICC): 1/50
Immunofluorescence (IF): 1/50
Immunohistochemistry-paraffin (IHC-P): 1/100-1/400
Flow cytometry (FC): 1/50
Target
- Alternative Names
- Filamin A; Endothelial Actin-Binding Protein; Actin Binding Protein 280; Non-Muscle Filamin; Filamin A, Alpha; Alpha-Filamin; Filamin-1; ABP-280; FLN-A; FLN1; FLN; Filamin A, Alpha (Actin Binding Protein 280); Actin-Binding Protein 280; Alpha Filamin; EC 2.1.1.43;
- Gene ID
- 2316
- UniProt ID
- P21333
- Long Name
- Filamin A
- Cellular Localization
- Cytoplasm
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2386z | Mouse Anti-FLNA Recombinant Antibody (clone 18G9) | WB, ELISA, IHC | Mouse IgG1, κ |
| MRO-0590-CN | Rabbit Anti-FLNA Recombinant Antibody (clone CBACN-226) | WB, IF, IHC, FC | Rabbit IgG |
| ZG-0670J | Rabbit Anti-FLNA Recombinant Antibody (clone 1B2) | ELISA, IHC | Rabbit IgG |
| VS3-QX432 | Mouse Anti-FLNA Recombinant Antibody (clone 1273CT424.104.153) | WB | Mouse IgG1 |
| VS3-CJ776 | Rabbit Anti-FLNA Recombinant Antibody (VS3-CJ776) | WB, ICC, IF, IHC, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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