CytoStream™ Rabbit Anti-FSCN1 Recombinant Antibody (VS13-YC424)
CAT#: VS13-YC424
The CytoStream™ Rabbit Anti-FSCN1 Recombinant Antibody is specific for human, mouse and rat FSCN1. FSCN1, an actin-binding protein, organizes cellular actin structures, influencing migration and adhesion, with overexpression linked to cancer metastasis and appearing in Hodgkin's lymphoma markers. The anti-FSCN1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35991/if_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35991/267_C2_2_blue_red_green.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35991/265_C2_1_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glial cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5723/159112_B_9_5.jpg
Normal Tissue
Figure 5 Cerebellum
Granular cells - cytoplasm/membrane
Staining:High
Intensity: Strong
Granular cells - nucleus
Staining:High
Intensity: Strong
Molecular layer cells - cytoplasm/membrane
Staining:High
Intensity: Strong
Molecular layer cells - nucleus
Staining:High
Intensity: Strong
Processes in granular layer
Staining:High
Intensity: Strong
Processes in molecular layer
Staining:High
Intensity: Strong
Processes in white matter
Staining:High
Intensity: Strong
White matter cells - cytoplasm/membrane
Staining:High
Intensity: Strong
White matter cells - nucleus
Staining:High
Intensity: Strong
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5723/159112_B_7_8.jpg
Normal Tissue
Figure 6 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5723/159112_A_7_3.jpg
Normal Tissue
Figure 7 Kidney
Bowman's capsule
Staining:Medium
Intensity: Moderate
Quantity:>75%
Cells in glomeruli
Staining:High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5723/159112_A_7_5.jpg
Normal Tissue
Figure 8 Testis
Sertoli cells
Staining:High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5723/159112_A_5_6.jpg
Normal Tissue
Figure 9 Lymph node
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5723/159112_A_7_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (BEWO, Hep G2, K-562, NB-4, PC-3, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000075618-FSCN1
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Specifications
- Immunogen
- Recombinant human Fascin, aa 221-389.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat FSCN1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC, IF, IHC-P, FC, IP
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/2000
Immunocytochemistry (ICC): 1/50-1/200
Immunofluorescence (IF): 1/50-1/200
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- Fascin Actin-Bundling Protein 1; 55 KDa Actin-Bundling Protein; FAN1; P55; SNL; HSN; Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus); Singed (Drosophila)-Like (Sea Urchin Fascin Homolog Like);
- Gene ID
- 6624
- UniProt ID
- Q16658
- Long Name
- Fascin Actin-Bundling Protein 1
- Cellular Localization
- Cytoskeleton; Stress fiber; Cytosol; Cell cortex; Filopodium; Invadopodium; Microvillus; Cell junction
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "FSCN1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1354 | Hi-Affi™ Rabbit Anti-FSCN1 Recombinant Antibody (clone DS1354AB) | FC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0570-CN | Rabbit Anti-FSCN1 Recombinant Antibody (clone JM12-53) | WB, IF, IHC, IP, FC | Rabbit IgG |
| FAMAB-1136CQ | Mouse Anti-FSCN1 Recombinant Antibody (clone SAIC-32C-205) | Immuno-MRM, ELISA | Mouse IgG1 |
| ZG-0031C | Mouse Anti-FSCN1 Recombinant Antibody (clone ABT-FASN) | IHC-P, IF | Mouse IgG |
| ZG-0032C | Mouse Anti-FSCN1 Recombinant Antibody (clone PT1978) | IHC-P, IF, ICC | Mouse IgG |
| VS3-FY564 | Recombinant Mouse Anti-FSCN1 Antibody (clone 8D7-7E10-6D8) | IHC-P | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC425 | CytoStream™ Rabbit Anti-FSCN1 Polyclonal Antibody (VS13-YC425) | WB, IHC, IF, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2652 | Anti-FSCN1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2653 | Anti-Mouse FSCN1 Immunohistochemistry Kit | IHC |
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