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    CytoStream™ Rabbit Anti-FSCN1 Recombinant Antibody (VS13-YC424) (CAT#: VS13-YC424)

    The CytoStream™ Rabbit Anti-FSCN1 Recombinant Antibody is specific for human, mouse and rat FSCN1. FSCN1, an actin-binding protein, organizes cellular actin structures, influencing migration and adhesion, with overexpression linked to cancer metastasis and appearing in Hodgkin's lymphoma markers. The anti-FSCN1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line A-431
    Figure 1 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35991/if_selected.jpg
    Figure 2 IF staining of human cell line U-2 OS
    Figure 2 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35991/267_C2_2_blue_red_green.jpg
    Figure 3 IF staining of human cell line U-251 MG
    Figure 3 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35991/265_C2_1_blue_red_green.jpg
    Normal Tissue
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Glial cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5723/159112_B_9_5.jpg
    Figure 5 Cerebellum
    Figure 5 Cerebellum
    (Granular cells - cytoplasm/membrane
    Staining:High
    Intensity: Strong
    Granular cells - nucleus
    Staining:High
    Intensity: Strong
    Molecular layer cells - cytoplasm/membrane
    Staining:High
    Intensity: Strong
    Molecular layer cells - nucleus
    Staining:High
    Intensity: Strong
    Processes in granular layer
    Staining:High
    Intensity: Strong
    Processes in molecular layer
    Staining:High
    Intensity: Strong
    Processes in white matter
    Staining:High
    Intensity: Strong
    White matter cells - cytoplasm/membrane
    Staining:High
    Intensity: Strong
    White matter cells - nucleus
    Staining:High
    Intensity: Strong)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5723/159112_B_7_8.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5723/159112_A_7_3.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Bowman's capsule
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Cells in glomeruli
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5723/159112_A_7_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Sertoli cells
    Staining:High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5723/159112_A_5_6.jpg
    Figure 9 Lymph node
    Figure 9 Lymph node
    (Non-germinal center cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5723/159112_A_7_8.jpg
    RNA Expression
    Figure 10 RNA cell line category: Cell line enhanced (BEWO, Hep G2, K-562, NB-4, PC-3, SH-SY5Y)
    Figure 10 RNA cell line category: Cell line enhanced (BEWO, Hep G2, K-562, NB-4, PC-3, SH-SY5Y)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000075618-FSCN1

    Specifications

    • Immunogen
    • Recombinant human Fascin, aa 221-389.
    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human, Mouse and Rat FSCN1
    • Species Reactivity
    • Human, Mouse, Rat
    • Applications
    • WB, ICC, IF, IHC-P, FC, IP
    • Conjugate
    • NONE

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Protein A purified
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
    • Preservative
    • 0.05% Sodium azide
    • Storage
    • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Shipping with ice pack.

    Applications

    • Application Notes
    • Western blot (WB): 1/500-1/2000
      Immunocytochemistry (ICC): 1/50-1/200
      Immunofluorescence (IF): 1/50-1/200
      Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
      Flow cytometry (FC): 1/50-1/100

    Target

    • Alternative Names
    • Fascin Actin-Bundling Protein 1; 55 KDa Actin-Bundling Protein; FAN1; P55; SNL; HSN; Fascin Homolog 1, Actin-Bundling Protein (Strongylocentrotus Purpuratus); Singed (Drosophila)-Like (Sea Urchin Fascin Homolog Like);
    • Long Name
    • Fascin Actin-Bundling Protein 1
    • Cellular Localization
    • Cytoskeleton; Stress fiber; Cytosol; Cell cortex; Filopodium; Invadopodium; Microvillus; Cell junction

    Recommended Products

    Secondary Antibody

    Isotype Control

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "FSCN1"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Rabbit Monoclonal Antibody Products IgG Antibody Products Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
    CAT Product Name Application Type
    MOR-1354 Hi-Affi™ Rabbit Anti-FSCN1 Recombinant Antibody (clone DS1354AB) FC, WB Rabbit IgG

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