Anti-GAS1 (clone W24V100) Recombinant Antibody Coupled Liposome (VS-1024-FY102) (CAT#: VS-1024-FY102)

• Potential Clinical Applications
• Glioma

• Clone
• W24V100

• Antibody Type
• IgG

• Antibody Host
• Mouse

• Antibody Reactivity
• Human

• Antibody Description
• This is a recombinant mouse monoclonal antibody that was designed to specifically bind to human Growth Arrest Specific 1 (GAS1). GAS1 is a protein that plays a crucial role in regulating cell growth and development. By targeting GAS1, this monoclonal antibody can potentially modulate the signaling pathways associated with cell proliferation and differentiation.

• Storage
• See in the COA

• Storage Shelf Time
• See in the COA

• Target
• GAS1

• Introduction
• Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.

• Alternative Names
• GAS1; Growth arrest-specific protein 1 precursor

• Full Name
• Growth Arrest Specific 1

• Gene ID
• 2619

• UniProt ID
• P54826

• Cellular Localization
• Cell membrane

• Post Translation Modifications
• Glycosylation at Asn117 ( NX_P54826 [NX_P54826-1] )
  Ubiquitination at Lys192 ( NX_P54826 [NX_P54826-1] )
  Modification sites at PhosphoSitePlus ( P54826 )
  Glycosylation from GlyGen (P54826) 1 site, 1 N-linked glycan (1 site)

• Protein Refseq
• NP_002039.2

• Function
• Specific growth arrest protein involved in growth suppression.
  Blocks entry to S phase.
  Prevents cycling of normal and transformed cells.
  Binds 20(S)-hydroxycholesterol (20(S)-OHC) (By similarity).

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