Mouse Anti-GOT2 Recombinant Antibody (VS3-CJ206)
CAT#: VS3-CJ206
This product is a mouse antibody that recognizes GOT2.
Gene Expression
Normal Tissue
Figure 1 Heart muscle
High expression in heart muscle
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18139/41977_B_4_6_val_selected.jpg
Normal Tissue
Figure 2 IHC staining of human heart muscle
Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in cardiomyocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/58537/170840_B_4_6_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18139/41977_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18139/41977_A_7_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18139/41977_A_8_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Collecting ducts Staining: High Intensity: Strong Quantity:>75% Distal tubules Staining: High Intensity: Strong Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18139/41977_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18139/41977_A_4_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/18139/41977_A_7_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000125166-GOT2
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Specifications
- Immunogen
- Recombinant protein corresponding to fragment (aa/225-430) GOT2
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human and Mouse GOT2
- Species Reactivity
- Human, Mouse
- Applications
- WB, ELISA
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (lot specific)
- Buffer
- Citrate-tris-HCl buffer, pH7.0.
- Preservative
- 0.02% Proclin 300
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- KAT4; DEE82; KATIV; KYAT4; mitAAT
- Gene ID
- 2806
- UniProt ID
- P00505
- Sequence Similarities
- Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
- Cellular Localization
- Cell membrane, Membrane, Mitochondrion
- Protein Refseq
- NP_001273149.1; NP_002071.2
- Function
- Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
See other products for "GOT2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1752MZ | Recombinant Mouse Anti-Human GOT2 Antibody | ELISA, WB | Mouse antibody |
| ZG-0257F | Mouse Anti-GOT2 Recombinant Antibody (ZG-0257F) | WB, IF, ELISA | Mouse IgG |
| ZG-0391J | Mouse Anti-GOT2 Recombinant Antibody (ZG-0391J) | WB | Mouse IgG |
| VS3-QX473 | Mouse Anti-GOT2 Recombinant Antibody (clone 6C6-C7-G7) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS7-HM1016 | Mouse Anti-GOT2 Recombinant Antibody (clone CBL326HM) | WB, IF, ICC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1481 | Hi-Affi™ Rabbit Anti-GOT2 Recombinant Antibody (clone DS1481AB) | WB, IHC-P, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY229 | Mouse Anti-NHP GOT2 Recombinant Antibody (clone 3E9) | WB, IF, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY941 | Anti-GOT2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2872 | Anti-Mouse GOT2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2871 | Anti-Human GOT2 Immunohistochemistry Kit | IHC |
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