AibGenesis™ Rabbit Anti-GPX3 Recombinant Antibody (AibG-Rb-GP446)
CAT#: VS-0426-FY446
Engineered through our AI-powered antibody discovery platform, this Rabbit IgG targets GPX3. Validated for WB and IHC in Mouse and Rat, it delivers high-fidelity performance for monitoring plasma glutathione peroxidase and its essential antioxidant function in the vascular system and extracellular environment.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human kidney
Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69456/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69456/150676_B_7_5.jpg
Normal Tissue
Figure 3 Small intestine
Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69456/150676_A_4_2.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69456/150676_A_7_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69456/150676_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69456/150676_A_6_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enriched (ASC diff)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000211445-GPX3
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Specifications
- Immunogen
- Mouse
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Mouse GPX3
- Species Reactivity
- Mouse, Rat
- Clone
- AibG-Rb-GP446
- Applications
- Western Blot, Immunohistochemistry
- Conjugate
- Unconjugated, Biotin and FITC are available.
- Related Disease
- Keshan Disease
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Format
- Liquid
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% Glycerol, 0.05% Protective protein
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (1:500-1:2000), Immunohistochemistry (1:200-1:500)
Target
- Alternative Names
- GPx; EGPx; GSHPx-3; GSHPx-P; AA960521
- Gene ID
- 14778
- UniProt ID
- P23764
- Long Name
- Glutathione Peroxidase 3
- Sequence Similarities
- Belongs to the glutathione peroxidase family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- The N-terminus is blocked. ( P22352-GPX3_HUMAN )
Modification sites at PhosphoSitePlus ( P22352 )
Modification sites at neXtProt
- Protein Refseq
- NP_001316719.1; NP_002075.2
- Function
- Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "GPX3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2587z | Mouse Anti-GPX3 Recombinant Antibody (clone 24G9) | WB, ELISA, IP | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0761MZ | Recombinant Mouse Anti-Human GPX3 Antibody (clone 66B) | ELISA | Mouse antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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