Rabbit Anti-GRB7 Recombinant Antibody (clone R03-7M6) (CAT#: VS3-XY3372)

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Mouse and Rat GRB7

• Species Reactivity
• Human, Mouse, Rat

• Clone
• R03-7M6

• Applications
• WB, IHC-P

• Related Disease
• Breast Cancer; Gastric Cancer

• Clonality
• Monoclonal

• Aggregation
• < 5%

• Format
• Liquid

• Buffer
• PBS (pH 7.4), 150 mM NaCl and 50% glycerol

• Preservative
• 0.02% sodium azide

• Storage
• Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Shipping
• Ice packs

• Application Notes
• WB: 1/500-1/1000
  IHC: 1/50-1/100

• Alternative Names
• Growth factor receptor bound protein 7

• Gene ID
• 2886

• UniProt ID
• Q14451

• Long Name
• Growth factor receptor bound protein 7

• Cellular Localization
• Cytoplasm, Cell junction, focal adhesion

• Post Translation Modifications
• Modification sites at PhosphoSitePlus (Q14451)
  Modification sites at neXtProt (NX_Q14451)
  Glycosylation from GlyGen (Q14451) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• NP_001025173.1; NP_001229371.2

• Function
• Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling.
  Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3.
  Promotes activation of HRAS.
  Plays a role in signal transduction in response to EGF.
  Plays a role in the regulation of cell proliferation and cell migration.
  Plays a role in the assembly and stability of RNA stress granules.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

Secondary Antibody

• 2RD-A1473-YJ
• Goat Anti-Rabbit IgG-F(ab')2 Secondary antibody

Select a product category from the dropdown menu below to view related products.