Human Anti-HAMP Recombinant Antibody (clone 15E1 N57H)
CAT#: VS-0724-YC27
Provided is a recombinant antibody 15E1 N57H that binds hepcidin. 15E1 N57H demonstrated lower binding affinity for hepcidin at pH 6.0 compared to pH 7.4.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enriched (Hep G2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000105697-HAMP
❮
❯
Specifications
- Immunogen
- KLH-conjugated human hepcidin
- Host Species
- Human
- Derivation
- Hybridoma
- Type
- Human IgG2
- Specificity
- Human hepcidin
- Species Reactivity
- Human
- Clone
- 15E1 N57H
- Applications
- ELISA, SPR
Product Property
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- HEPC; PLTR; HFE2B; LEAP1
- Gene ID
- 57817
- UniProt ID
- P81172
- Long Name
- Hepcidin
- Sequence Similarities
- Belongs to the hepcidin family.
- Cellular Localization
- Secreted
- Protein Refseq
- NP_066998.1
- Function
- Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues.
Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma.
Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.
Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria.
Active against the fungus C.albicans.
No activity against P.aeruginosa.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0724-YC27. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "HAMP"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-430 | Recombinant Anti-human HAMP Antibody | WB, IP, FuncS | IgG |
| MHH-430 | Recombinant Human Anti-human HAMP Antibody | ELISA, WB, IP, FuncS | IgG |
| MOB-2451MZ | Recombinant Mouse Anti-Human HAMP Antibody (clone 1F9) | IHC-P, WB | Mouse antibody |
| HPAB-0915-WJ | Mouse Anti-HAMP Recombinant Antibody (HPAB-0915-WJ) | Inhib | Mouse IgG1 |
| VS-0224-XY59 | Mouse Anti-HAMP Recombinant Antibody (VS-0224-XY59) | ELISA, WB, ICC, IHC-Fr, IHC-P | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-430-F(E) | Recombinant Anti-human HAMP Antibody Fab Fragment | FC, IP, FuncS | Fab |
| HPAB-0226-YC-F(E) | Mouse Anti-HAMP Recombinant Antibody; Fab Fragment (HPAB-0226-YC-F(E)) | ELISA, Neut | Mouse Fab |
| HPAB-0227-YC-F(E) | Rat Anti-HAMP Recombinant Antibody; Fab Fragment (HPAB-0227-YC-F(E)) | ELISA | Rat Fab |
| HPAB-0228-YC-F(E) | Human Anti-HAMP Recombinant Antibody; Fab Fragment (HPAB-0228-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-0915-WJ-F(E) | Mouse Anti-HAMP Recombinant Antibody; Fab Fragment (HPAB-0915-WJ-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-430-S(P) | Recombinant Anti-human HAMP Antibody scFv Fragment | FC, RIA, Biosensors, FuncS | scFv |
| MHH-430-S(P) | Recombinant Human Anti-human HAMP Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
| HPAB-0226-YC-S(P) | Mouse Anti-HAMP Recombinant Antibody; scFv Fragment (HPAB-0226-YC-S(P)) | ELISA, Neut | Mouse scFv |
| HPAB-0227-YC-S(P) | Rat Anti-HAMP Recombinant Antibody; scFv Fragment (HPAB-0227-YC-S(P)) | ELISA | Rat scFv |
| HPAB-0915-WJ-S(P) | Mouse Anti-HAMP Recombinant Antibody; scFv Fragment (HPAB-0915-WJ-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-338CL | Human Anti-HAMP Recombinant Antibody (TAB-338CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0306CL | Mouse Anti-HAMP Recombinant Antibody (TAB-0306CL) | ELISA, Neut, FC, Ferritin assay, FuncS | Chimeric (mouse/human) |
| TAB-0307CL | Mouse Anti-HAMP Recombinant Antibody (TAB-0307CL) | ELISA, Neut, FC, Ferritin assay, FuncS | Chimeric (mouse/human) |
| TAB-0308CL | Mouse Anti-HAMP Recombinant Antibody (TAB-0308CL) | ELISA, Neut, FC, Ferritin assay, FuncS | Chimeric (mouse/human) |
| TAB-0309CL | Mouse Anti-HAMP Recombinant Antibody (TAB-0309CL) | ELISA, Neut, FC, Ferritin assay, FuncS | Chimeric (mouse/human) |
| TAB-0306CL-S(P) | Mouse Anti-HAMP Recombinant Antibody; scFv Fragment (TAB-0306CL-S(P)) | ELISA, Neut, FC, Ferritin assay, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-080 | Recombinant Human Anti-Hepcidin Antibody | WB, ELISA, FuncS | IgG |
| PABX-080-S (P) | Recombinant Human Anti-Hepcidin Antibody scFv Fragment | WB, ELISA, FuncS | scFv |
| PABX-080-F (E) | Recombinant Human Anti-Hepcidin Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3052 | Anti-HAMP Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC139 | Recombinant Anti-HAMP Eliminating Antibody, pH-Sensitive (VS-0625-YC139) | Antigen-Sweeping In Vivo. | Human IgG1 |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: FuncS, IF, Neut, ELISA, FC, IP, WB
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application:
Application: ELISA, Neut, FuncS
Application: ELISA, FuncS, IHC, IF, FC, ADCC
Application: ELISA, IHC, IF, IP, FC, FuncS
Application: ELISA, PD, Activ, PK, Stim
Application: FC, IA, IF, IP, IHC, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
