DrugMonitor™ Anti-HCG Antibody (VS-1224-YC276)
CAT#: VS-1224-YC276
Human chorionic gonadotropin (HCG) is a polypeptide hormone produced by the human placenta. As a drug, chorionic gonadotropin is a highly purified, pyrogen-free preparation obtained from the urine of pregnant females. The DrugMonitor™ Anti-HCG Antibody (VS-1224-YC276) is an anti-drug antibody (ADA) against HCG. This drug-based antibody is raised in mice immunized with the Chorionic Gonadotropin (Human). The anti-HCG antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the HCG in samples.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38925/537_C10_3_selected.jpg
Normal Tissue
Figure 2 IHC staining of human placenta
Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38925/ihc_selected.jpg
Normal Tissue
Figure 3 Placenta
Trophoblastic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38934/101364_A_2_7.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (BEWO, U-251 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000189052-CGB5
❮
❯
Specifications
- Host Animal
- Mouse
- Specificity
- Chorionic Gonadotropin
- Target
- HCG
- Immunogen
- Human Chorionic Gonadotropin
- Type
- Mouse IgG
- Species Reactivity
- Human
- Purity
- >95%
- Purification
- Protein G
- Applications
- ELISA, PK/PD, ADA control
- Format
- Liquid
- Concentration
- Batch-dependent
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for 1-2 weeks and at -20°C for 1 year. Avoid repeated freezing and thawing.
- Generic name
- Chorionic Gonadotropin
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Datasheet
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COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-441 | Recombinant Anti-human hCG Antibody | ELISA, WB, FC, FuncS | IgG |
| MHH-441 | Recombinant Human Anti-human hCG Antibody | ELISA, WB, FuncS | IgG |
| PABC-056 | Mouse Anti-hCG Recombinant Antibody (clone 3A2) | WB, IHC, IF, FuncS | Mouse IgG |
| HPAB-0353-YJ | Mouse Anti-HCG Recombinant Antibody (HPAB-0353-YJ) | ELISA, Inhib, Immunocontraception | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-441-F(E) | Recombinant Anti-human hCG Antibody Fab Fragment | IF, FuncS | Fab |
| MHH-441-F(E) | Recombinant Human Anti-human hCG Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| PFBC-056 | Mouse Anti-hCG Recombinant Antibody (clone 3A2); Fab Fragment | WB, IHC, IF, FuncS | Mouse Fab |
| HPAB-0353-YJ-F(E) | Mouse Anti-HCG Recombinant Antibody; Fab Fragment (HPAB-0353-YJ-F(E)) | ELISA, Inhib, Immunocontraception | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-441-S(P) | Recombinant Anti-human hCG Antibody scFv Fragment | WB, FC, FuncS | scFv |
| MHH-441-S(P) | Recombinant Human Anti-human hCG Antibody scFv Fragment | WB, IP, FuncS | scFv |
| PSBC-056 | Mouse Anti-hCG Recombinant Antibody (clone 3A2); scFv Fragment | WB, IHC, IF, FuncS | Mouse scFv |
| HPAB-0353-YJ-S(P) | Mouse Anti-HCG Recombinant Antibody; scFv Fragment (HPAB-0353-YJ-S(P)) | ELISA, Inhib, Immunocontraception | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-017CT | Goat Anti-Human hCG Recombinant Antibody | ELISA, WB | |
| TAB-017CT-S(P) | Anti-Human hCG Recombinant Antibody scFv Fragment | ELISA, WB | |
| TAB-017CT-F(E) | Anti-Human hCG Recombinant Antibody Fab Fragment | ELISA, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018CT | Anti-Human hCG Recombinant Antibody (PIPP) | EMSA, Inhib, Neut, ELISA, FC | Humanized antibody |
| TAB-018CT-S(P) | Anti-Human hCG Recombinant Antibody scFv Fragment (PIPP) | EMSA, Inhib, ELISA, FC | Humanized antibody |
| TAB-018CT-F(E) | Anti-Human hCG Recombinant Antibody Fab Fragment (PIPP) | ELISA, Inhibition, FC | Humanized antibody |
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