Anti-Human hCG Recombinant Antibody Fab Fragment (PIPP)
CAT#: TAB-018CT-F(E)
Recombinant monoclonal antibody Fab fragment (PIPP) to hCG. This antibody intended for the prophylaxis and treatment studies of T- Lymphoblastic leukemia.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38925/537_C10_3_selected.jpg
Normal Tissue
Figure 2 IHC staining of human placenta
Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38925/ihc_selected.jpg
Normal Tissue
Figure 3 Placenta
Trophoblastic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/38934/101364_A_2_7.jpg
RNA Expression
Figure 4 RNA cell line category: Group enriched (BEWO, U-251 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000189052-CGB5
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Specifications
- Host Species
- Human
- Derivation
- Hybridoma cell line
- Type
- Humanized antibody
- Antibody Isotype
- IgG1, κ
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- PIPP
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Inhibition; Flow Cytometry
- Related Disease
- T- Lymphoblastic leukemia
Target
- Alternative Names
- Hcg; Chorionic gonadotropin; CGA; CGB; anti-hCG
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Ideal For T-ALL Studies
We are investigating T-Lymphoblastic leukemia, and this anti-hCG Fab fragment (PIPP) has been a unique tool for our prophylaxis studies. The Fab format is advantageous for certain assays where we need to avoid Fc-mediated effects. It works well in ELISA and inhibition assays.
Specific And Pure Fab Fragment
The recombinant production of this Fab fragment ensures high purity and consistency. We used it in Flow Cytometry to detect hCG binding, and the results were clear. It is a high-quality humanized antibody fragment suitable for specialized research applications.
Q&As
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Why is this antibody supplied as a Fab fragment?
A: The Fab fragment format (clone PIPP) lacks the Fc region, which reduces non-specific binding to Fc receptors on cells. This is particularly useful for specific applications like Inhibition studies and Flow Cytometry where Fc interference must be avoided.
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What is the intended research use for this antibody?
A: This recombinant antibody fragment targets human hCG and is intended for research into the prophylaxis and treatment of T-Lymphoblastic leukemia. It can be used in ELISA, Inhibition, and Flow Cytometry assays.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone PIPP"
- CAT
- Product Name
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Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-441 | Recombinant Anti-human hCG Antibody | ELISA, WB, FC, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-441-F(E) | Recombinant Anti-human hCG Antibody Fab Fragment | IF, FuncS | Fab |
| CAT | Product Name | Application | Type |
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| MOB-441-S(P) | Recombinant Anti-human hCG Antibody scFv Fragment | WB, FC, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-441 | Recombinant Human Anti-human hCG Antibody | ELISA, WB, FuncS | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-441-F(E) | Recombinant Human Anti-human hCG Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-441-S(P) | Recombinant Human Anti-human hCG Antibody scFv Fragment | WB, IP, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-056 | Mouse Anti-hCG Recombinant Antibody (clone 3A2) | WB, IHC, IF, FuncS | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-056 | Mouse Anti-hCG Recombinant Antibody (clone 3A2); Fab Fragment | WB, IHC, IF, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-056 | Mouse Anti-hCG Recombinant Antibody (clone 3A2); scFv Fragment | WB, IHC, IF, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-017CT | Goat Anti-Human hCG Recombinant Antibody | ELISA, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018CT | Anti-Human hCG Recombinant Antibody (PIPP) | EMSA, Inhib, Neut, ELISA, FC | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-017CT-S(P) | Anti-Human hCG Recombinant Antibody scFv Fragment | ELISA, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-018CT-S(P) | Anti-Human hCG Recombinant Antibody scFv Fragment (PIPP) | EMSA, Inhib, ELISA, FC | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-017CT-F(E) | Anti-Human hCG Recombinant Antibody Fab Fragment | ELISA, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0353-YJ | Mouse Anti-HCG Recombinant Antibody (HPAB-0353-YJ) | ELISA, Inhib, Immunocontraception | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0353-YJ-S(P) | Mouse Anti-HCG Recombinant Antibody; scFv Fragment (HPAB-0353-YJ-S(P)) | ELISA, Inhib, Immunocontraception | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0353-YJ-F(E) | Mouse Anti-HCG Recombinant Antibody; Fab Fragment (HPAB-0353-YJ-F(E)) | ELISA, Inhib, Immunocontraception | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1224-YC276 | DrugMonitor™ Anti-HCG Antibody (VS-1224-YC276) | ELISA, PK/PD, ADA control | Mouse IgG |
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