Recombinant monoclonal antibody clone PIPP to hCG. The antibody PIPP was generated in a hybridoma cell line. This antibody intended for the prophylaxis and treatment studies of T- Lymphoblastic leukemia.
Figure 1 Electrophoretic mobility shift assay of affinity purified recombinant proteins.
Purified scFv, diabody or chimeric mAb PIPP were incubated with increasing amounts of HCG.
Kathuria, S., Sriraman, R., Nath, R., Sack, M., Pal, R., Artsaenko, O., ... & Finnern, R. (2002). Efficacy of plant-produced recombinant antibodies against HCG. Human Reproduction, 17(8), 2054-2061.
Figure 2 Inhibition of HCG induced production of testosterone by Leydig cells through plant-expressed recombinant scFv, diabody and chimeric mAb PIPP.
All three plant-expressed recombinant proteins were able to inhibit the stimulation of HCG production in Leydig cells.
Kathuria, S., Sriraman, R., Nath, R., Sack, M., Pal, R., Artsaenko, O., ... & Finnern, R. (2002). Efficacy of plant-produced recombinant antibodies against HCG. Human Reproduction, 17(8), 2054-2061.
Figure 3 In-vivo neutralization of HCG-induced increase in uterine weight by plant-expressed chimeric mAb PIPP.
Plant-produced recombinant antibodies were able to neutralize HCG in vivo.
Kathuria, S., Sriraman, R., Nath, R., Sack, M., Pal, R., Artsaenko, O., ... & Finnern, R. (2002). Efficacy of plant-produced recombinant antibodies against HCG. Human Reproduction, 17(8), 2054-2061.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-441 | Recombinant Anti-human hCG Antibody | ELISA, WB, FC, FuncS | IgG |
MHH-441 | Recombinant Human Anti-human hCG Antibody | ELISA, WB, FuncS | IgG |
PABC-056 | Mouse Anti-hCG Recombinant Antibody (clone 3A2) | WB, IHC, IF, FuncS | Mouse IgG |
HPAB-0353-YJ | Mouse Anti-HCG Recombinant Antibody (HPAB-0353-YJ) | ELISA, Inhib, Immunocontraception | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-441-F(E) | Recombinant Anti-human hCG Antibody Fab Fragment | IF, FuncS | Fab |
MHH-441-F(E) | Recombinant Human Anti-human hCG Antibody Fab Fragment | ELISA, WB, FuncS | Fab |
PFBC-056 | Mouse Anti-hCG Recombinant Antibody (clone 3A2); Fab Fragment | WB, IHC, IF, FuncS | Mouse Fab |
HPAB-0353-YJ-F(E) | Mouse Anti-HCG Recombinant Antibody; Fab Fragment (HPAB-0353-YJ-F(E)) | ELISA, Inhib, Immunocontraception | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-441-S(P) | Recombinant Anti-human hCG Antibody scFv Fragment | WB, FC, FuncS | scFv |
MHH-441-S(P) | Recombinant Human Anti-human hCG Antibody scFv Fragment | WB, IP, FuncS | scFv |
PSBC-056 | Mouse Anti-hCG Recombinant Antibody (clone 3A2); scFv Fragment | WB, IHC, IF, FuncS | Mouse scFv |
HPAB-0353-YJ-S(P) | Mouse Anti-HCG Recombinant Antibody; scFv Fragment (HPAB-0353-YJ-S(P)) | ELISA, Inhib, Immunocontraception | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-017CT | Goat Anti-Human hCG Recombinant Antibody | ELISA, WB | |
TAB-017CT-S(P) | Anti-Human hCG Recombinant Antibody scFv Fragment | ELISA, WB | |
TAB-017CT-F(E) | Anti-Human hCG Recombinant Antibody Fab Fragment | ELISA, WB |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-018CT-S(P) | Anti-Human hCG Recombinant Antibody scFv Fragment (PIPP) | EMSA, Inhib, ELISA, FC | Humanized antibody |
TAB-018CT-F(E) | Anti-Human hCG Recombinant Antibody Fab Fragment (PIPP) | ELISA, Inhibition, FC | Humanized antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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