Mouse Anti-HCV Core Protein Recombinant Antibody (clone AA10) (CAT#: FAMAB-0301JF)

Recombinant monoclonal antibody specially binds to HCV core. AA10 is a mouse monoclonal antibody that can be potentially used in the immunotherapy of HCV infection.


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Inhib

Figure 1 Effects of intrabodies on the production of HCV.

Figure 1 Effects of intrabodies on the production of HCV.

Huh7.5.1 cells were transfected with each intrabody-encoding plasmid along with Pol I-driven HCV genome plasmid pHHJFH1am. Infectious titres of HCVcc in the supernatants were determined at 5 days post-infection (p.i.).

Suzuki, R., Saito, K., Matsuda, M., Sato, M., Kanegae, Y., Shi, G., Watashi, K., Aizaki, H., Chiba, J., Saito, I., Wakita, T., & Suzuki, T. (2016). Single-domain intrabodies against hepatitis C virus core inhibit viral propagation and core-induced NFκB activation. The Journal of general virology, 97(4), 887–892.


Specifications

  • Immunogen
  • Core expressed by bacteria
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1
  • Specificity
  • HCV core
  • Species Reactivity
  • HCV
  • Clone
  • AA10
  • Applications
  • IB, IP, ELISA, FuncS
  • Related Disease
  • HCV infection

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Hepatitis C virus; HCV; Hepatitis C virus core protein; HCV core protein

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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