AbPlus™ Anti-HDAC2 Magnetic Beads (CBACN-257) (CAT#: VS-0424-XY120)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-HDAC2 specific antibody (CBACN-257)

• Target
• HDAC2

• Immunogen
• C-terminus of human HDAC2

• Target Species
• Human, Mouse, Rat

• Antibody Clone
• CBACN-257

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

• Alternative Names
• Histone Deacetylase 2; EC 3.5.1.98; HD2; Transcriptional Regulator Homolog RPD3; YY1-Associated Factor 1; RPD3; YAF1

• Gene ID
• 3066

• UniProt ID
• Q92769

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