AbPlus™ Anti-HDAC2 Magnetic Beads (VS-0724-YC970)
CAT#: VS-0724-YC970
The AbPlus Anti-HDAC2 Magnetic Beads (VS-0724-YC970) is an innovative affinity resin which is bound with anti-HDAC2 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of HDAC2 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11727/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5054/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human hippocampus
Immunohistochemical staining of human hippocampus shows strong nuclear positivity in neuronal cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5054/ihc_selected.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: nuclear Non-germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5054/17525_A_8_8.jpg
Normal Tissue
Figure 5 Cerebral cortex
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5054/17525_B_7_5.jpg
Normal Tissue
Figure 6 Salivary gland
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5054/17525_B_2_1.jpg
Normal Tissue
Figure 7 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5054/17525_A_9_5.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196591-HDAC2
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-HDAC2 specific antibody
- Target
- HDAC2
- Immunogen
- Synthetic peptide corresponding to the C-terminus of the human HDAC2.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
- Alternative Names
- Histone Deacetylase 2; EC 3.5.1.98; HD2; Transcriptional Regulator Homolog RPD3; YY1-Associated Factor 1; RPD3; YAF1;
- Gene ID
- 3066
- UniProt ID
- Q92769
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Related Diseases
Alcoholism
Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "HDAC2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2296CT | Recombinant Mouse anti-Human HDAC2 Monoclonal antibody (FQS5045) | IHC-P, WB, IP, ChIP, ICC, IF | |
| MRO-1931-CN | Rabbit Anti-HDAC2 Polyclonal Antibody (MRO-1931-CN) | WB, IF, IHC, FC | Rabbit IgG |
| ZG-0709J | Rabbit Anti-HDAC2 Recombinant Antibody (clone 9E9) | ELISA, WB, IHC | Rabbit IgG |
| ZG-0710J | Rabbit Anti-HDAC2 Recombinant Antibody (clone 9H4) | ELISA, WB, IHC, IF | Rabbit IgG |
| VS1-YJ82 | Mouse Anti-HDAC2 Recombinant Antibody (clone 3F3) | WB, ICC, IF | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1574 | Rabbit Anti-HDAC2 Recombinant Antibody (clone DS1574AB) | WB, IHC-P, ICC, IF, FC, IP, IHC-Fr | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY120 | AbPlus™ Anti-HDAC2 Magnetic Beads (CBACN-257) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1000 | Anti-HDAC2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3095 | Anti-Mouse HDAC2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3094 | Anti-Human HDAC2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3096 | Anti-Rat HDAC2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC501 | CytoStream™ Rabbit Anti-HDAC2 Recombinant Antibody (VS13-YC501) | WB, ICC, IF, IHC-P, IP, FC | Rabbit IgG |
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