Mouse Anti-HDAC3 Monoclonal Antibody (clone 7G6C5)
CAT#: VS7-0425-WR22
This product is a mouse IgG2a antibody that binds to human HDAC3. 7G6C5 recognizes the specific domains AA: 224-428 on human HDAC3. This antibody can be used for WB and ICC assays.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52052/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5583/if_selected.jpg
Normal Tissue
Figure 3 IHC staining of human parathyroid gland
Immunohistochemical staining of human parathyroid gland shows moderate nuclear positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/72336/167035_A_2_8_selected.jpg
Normal Tissue
Figure 4 Testis
Sertoli cells Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5583/18273_A_4_6.jpg
Normal Tissue
Figure 5 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5583/18273_A_8_8.jpg
Normal Tissue
Figure 6 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5583/18273_B_7_5.jpg
Normal Tissue
Figure 7 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5583/18273_A_9_3.jpg
Normal Tissue
Figure 8 Urinary bladder
Urothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5583/18273_A_4_5.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171720-HDAC3
❮
❯
Specifications
- Immunogen
- Recombinant human HDAC3 (AA 224-428) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG2a
- Specificity
- Human HDAC3
- Species Reactivity
- Human
- Clone
- 7G6C5
- Molecule Class
- Enzyme
- Applications
- WB, ICC
- Conjugate
- Unconjugated
- Related Disease
- Cancer; Neurodegenerative Diseases; Inflammatory Diseases; Cardiovascular Diseases; Metabolic Disorders
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunocytochemistry: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- HD3; RPD3; KDAC3; RPD3-2
- Gene ID
- 8841
- UniProt ID
- O15379
- Long Name
- Histone deacetylase 3
- Cellular Localization
- Chromosome; Cytoplasm; Nucleus
- Post Translation Modifications
- Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_001341968.1
- Function
- Chromatin regulator; Hydrolase; Repressor
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS7-0425-WR22. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Related Diseases
Alcoholism
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "HDAC3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2420z | Mouse Anti-HDAC3 Recombinant Antibody (clone 43A11) | WB, ELISA, FC, ICC, IF, IHC | Mouse IgG1 |
| MRO-0738-CN | Mouse Anti-HDAC3 Recombinant Antibody (clone B2-G9) | WB, IF, IHC | Mouse IgG2b |
| VS1-YJ85 | Mouse Anti-HDAC3 Recombinant Antibody (clone 3G6) | WB, IP | Mouse IgG2a |
| VS4-WK211 | Mouse Anti-HDAC3 Recombinant Antibody (VS4-WK211) | ELISA, WB | Mouse IgG |
| VS7-0425-WR23 | Mouse Anti-HDAC3 Monoclonal Antibody (VS7-0425-WR23) | WB, IF, ICC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1575 | Rabbit Anti-HDAC3 Recombinant Antibody (clone DS1575AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1001 | Anti-HDAC3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3097 | Anti-Human HDAC3 Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: FC, Cyt, Stim, PP, Agonist
Application: WB, FC, IP, ELISA, Neut, FuncS, IF
-2.png)
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: WB, IHC, FC, Cyt, ELISA
Application: WB, ELISA, FuncS, Inhib, PK, IP, SPR
Application: Neut, ELISA, FuncS
Application: ELISA
Application: Neut, ELISA, IF, IP, FuncS, FC
Application: ELISA, FC, Inhib, IHC-Fr, WB, IP
Application: ELISA, FC, FuncS
Application: ELISA, WB
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
