Human Anti-HLA-DR Recombinant Antibody (clone DR4B117) (CAT#: HPAB-0210-WJ)
This product is a human antibody derived from phage display library targeting human HLA-DR. This antibody binds HLA-DR on the CD4 binding site instead of interfering with interaction of HLA-DR with cognate T cell receptor (TCR). It may induce conformational and/or spatial changes in the HLA-DR molecule hence preventing the interaction between HLA-DR and cognate T cell receptor or between HLA-DR and the T cell co-receptor CD4.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human IgG1
- Specificity
- Human HLA-DR
- Species Reactivity
- Human
- Clone
- DR4B117
- Applications
- ELISA, WB
- Related Disease
- Autoimmune diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- DR alpha chain precursor; DRB1; DRB4; HLA class II histocompatibility antigen; HLA class II histocompatibility antigen DR alpha chain; HLA DR1B; HLA DR3B; HLA DRA
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-503-F(E) | Recombinant Anti-human HLA-DR Antibody Fab Fragment | RIA, IF, FuncS | Fab |
| HPAB-M0498-YC-F(E) | Mouse Anti-HLA-DR Recombinant Antibody; Fab Fragment (HPAB-M0498-YC-F(E)) | ELISA, FC, Cyt | Mouse Fab |
| HPAB-M0499-YC-F(E) | Mouse Anti-HLA-DR Recombinant Antibody; Fab Fragment (HPAB-M0499-YC-F(E)) | ELISA, FC, Cyt | Mouse Fab |
| HPAB-0210-WJ-F(E) | Human Anti-HLA-DR Recombinant Antibody (clone DR4B117); Fab Fragment | ELISA, WB | Human Fab |
| HPAB-2054-FY-F(E) | Human Anti-HLA-DR Recombinant Antibody (clone I-2); Fab Fragment | FC | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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