Human Anti-HLA-DR Recombinant Antibody (clone HD4)

CAT#: HPAB-1155WJ

This product is a human antibody produced from mice which have human immunoglobulin γ chain (hIgγ) and human immunoglobulin light chain κ. This antibody can be used in studies of diseases caused by an HLA-DR-expressing cell and malignant tumors.

Published Data
Figure 1 A diagram shows the immunosuppressive activity of the purified human anti-HLA-DR monoclonal antibody on MLR. Figure 2 A diagram shows the life-extending effects of the purified human anti-HLA-DR monoclonal antibody on the tumor-bearing mouse model. Figure 3 A diagram shows the antibody-dependent cellular cytotoxicity (ADCC) of the purified human anti-HLA-DR monoclonal antibody. Figure 4 A diagram shows the complement-dependent cytotoxicity (CDC) of the purified human anti-HLA-DR monoclonal antibody.

Specifications

  • Immunogen
  • Human HLA-DR-expressing Cell
  • Host Species
  • Human
  • Type
  • Human IgG1
  • Specificity
  • Human HLA-DR
  • Species Reactivity
  • Human
  • Clone
  • HD4
  • Related Disease
  • Malignant tumors

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HLA-DR antibody has been reported in applications of Inhibition, Antibody-dependent Cell-mediated Cytotoxicity, Complement Mediated Cell Depletion.
    Inhib: 0.1 μg.

Target

  • Alternative Names
  • HLA-DR; Human Leukocyte Antigen-DR; L243
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

Certificate of Analysis Lookup

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VS-0425-FY116 Human Anti-HLA-DR (clone I-2) scFv-Fc Chimera IA Human IgG1, scFv-Fc
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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