Human Anti-HLA-DR Recombinant Antibody (clone HD4)
CAT#: HPAB-1155WJ
This product is a human antibody produced from mice which have human immunoglobulin γ chain (hIgγ) and human immunoglobulin light chain κ. This antibody can be used in studies of diseases caused by an HLA-DR-expressing cell and malignant tumors.
Published Data
Inhib
Figure 1 A diagram shows the immunosuppressive activity of the purified human anti-HLA-DR monoclonal antibody on MLR.
Inhib
Figure 2 A diagram shows the life-extending effects of the purified human anti-HLA-DR monoclonal antibody on the tumor-bearing mouse model.
Shows the effects attained when the dose is 0.1 μg/head.
ADCC
Figure 3 A diagram shows the antibody-dependent cellular cytotoxicity (ADCC) of the purified human anti-HLA-DR monoclonal antibody.
Shows the ADCC activities of HD8G1, HD8G2, HD8G2Ser, HD8G4, HD4G1, HD4G2Ser, and HD4G4.
CMCD
Figure 4 A diagram shows the complement-dependent cytotoxicity (CDC) of the purified human anti-HLA-DR monoclonal antibody.
Shows the CDC activities of HD8G1, HD8G2, HD8G2Ser, HD8G4, HD4G1, HD4G2Ser, and HD4G4.
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Specifications
- Immunogen
- Human HLA-DR-expressing Cell
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human HLA-DR
- Species Reactivity
- Human
- Clone
- HD4
- Applications
- Inhib, ADCC, CMCD
- Related Disease
- Malignant tumors
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HLA-DR antibody has been reported in applications of Inhibition, Antibody-dependent Cell-mediated Cytotoxicity, Complement Mediated Cell Depletion.
Inhib: 0.1 μg.
Target
- Alternative Names
- HLA-DR; Human Leukocyte Antigen-DR; L243
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone HD4"
- CAT
- Product Name
See other products for "HLA-DR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-503-F(E) | Recombinant Human Anti-human HLA-DR Antibody Fab Fragment | IF, Neut, FuncS | Fab |
| HPAB-0210-WJ-F(E) | Human Anti-HLA-DR Recombinant Antibody (clone DR4B117); Fab Fragment | ELISA, WB | Human Fab |
| HPAB-1155WJ-F(E) | Human Anti-HLA-DR Recombinant Antibody (clone HD4); Fab Fragment | ELISA | Human Fab |
| HPAB-1156WJ-F(E) | Human Anti-HLA-DR Recombinant Antibody (clone HD8); Fab Fragment | ELISA | Human Fab |
| HPAB-2054-FY-F(E) | Human Anti-HLA-DR Recombinant Antibody (clone I-2); Fab Fragment | FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-503-S(P) | Recombinant Human Anti-human HLA-DR Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
| HPAB-0050-YJ-S(P) | Human Anti-HLA-DR Recombinant Antibody (clone HD8G2Ser); scFv Fragment | ELISA, WB | Human scFv |
| HPAB-1542-FY-F(E) | Human Anti-HLA-DR Recombinant Antibody Fab Fragment (HPAB-1542-FY-F(E)) | WB, ELISA | Human Fab |
| HPAB-1206WJ-S(P) | Mouse Anti-HLA-DR Recombinant Antibody; scFv Fragment (HPAB-1206WJ-S(P)) | WB, FC | Mouse scFv |
| HPAB-2054-FY-S(P) | Human Anti-HLA-DR Recombinant Antibody (clone I-2); scFv Fragment | FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-094CT | Anti-Human HLA-DR Recombinant Antibody ( L243) | FC, Inhib | |
| TAB-094CT-S(P) | Anti-Human HLA-DR Recombinant Antibody scFv Fragment ( L243) | ELISA, WB | |
| TAB-094CT-F(E) | Anti-Human HLA-DR Recombinant Antibody Fab Fragment ( L243) | ELISA, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-095CT | Anti-Human HLA-DR β Recombinant Antibody (1D09C3) | FC, Inhib, WB, IHC | Humanized antibody |
| TAB-095CT-S(P) | Anti-Human HLA-DR β Recombinant Antibody scFv Fragment (1D09C3) | ELISA | Humanized antibody |
| TAB-095CT-F(E) | Anti-Human HLA-DR β Recombinant Antibody Fab Fragment (1D09C3) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0498-YC | Mouse Anti-HLA-DR Recombinant Antibody (HPAB-M0498-YC) | IHC, WB | Mouse IgG |
| HPAB-M0499-YC | Mouse Anti-HLA-DR Recombinant Antibody (HPAB-M0499-YC) | IHC, FuncS, FC | Mouse IgG |
| HPAB-0050-YJ | Human Anti-HLA-DR Recombinant Antibody (clone HD8G2Ser) | ELISA, WB | Human IgG2 |
| HPAB-1542-FY | Human Anti-HLA-DR Recombinant Antibody (HPAB-1542-FY) | WB, ELISA | Human IgG1 |
| HPAB-1156WJ | Human Anti-HLA-DR Recombinant Antibody (clone HD8) | WB, FC, ADCC, CMCD, Inhib | Human IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY116 | Human Anti-HLA-DR (clone I-2) scFv-Fc Chimera | IA | Human IgG1, scFv-Fc |
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