Human Anti-HLA-DR Recombinant Antibody (clone HD4) (CAT#: HPAB-1155WJ)
This product is a human antibody produced from mice which have human immunoglobulin γ chain (hIgγ) and human immunoglobulin light chain κ. This antibody can be used in studies of diseases caused by an HLA-DR-expressing cell and malignant tumors.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Inhib
Figure 1 A diagram shows the immunosuppressive activity of the purified human anti-HLA-DR monoclonal antibody on MLR.
Inhib
Figure 2 A diagram shows the life-extending effects of the purified human anti-HLA-DR monoclonal antibody on the tumor-bearing mouse model.
Shows the effects attained when the dose is 0.1 μg/head.
ADCC
Figure 3 A diagram shows the antibody-dependent cellular cytotoxicity (ADCC) of the purified human anti-HLA-DR monoclonal antibody.
Shows the ADCC activities of HD8G1, HD8G2, HD8G2Ser, HD8G4, HD4G1, HD4G2Ser, and HD4G4.
CMCD
Figure 4 A diagram shows the complement-dependent cytotoxicity (CDC) of the purified human anti-HLA-DR monoclonal antibody.
Shows the CDC activities of HD8G1, HD8G2, HD8G2Ser, HD8G4, HD4G1, HD4G2Ser, and HD4G4.
Specifications
- Immunogen
- Human HLA-DR-expressing Cell
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human HLA-DR
- Species Reactivity
- Human
- Clone
- HD4
- Applications
- Inhib, ADCC, CMCD
- Related Disease
- Malignant tumors
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HLA-DR antibody has been reported in applications of Inhibition, Antibody-dependent Cell-mediated Cytotoxicity, Complement Mediated Cell Depletion.
Inhib: 0.1 μg.
Target
- Alternative Names
- HLA-DR; Human Leukocyte Antigen-DR; L243
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
Mouse Antibody Products
Humanized Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-503 | Recombinant Anti-human HLA-DR Antibody | WB, IHC, FuncS | IgG |
| MOB-0001MZ | Recombinant Mouse Anti-Human HLA Class II Histocompatibility antigen DP, DQ, DR Antibody (clone DR4/44) | ELISA | Mouse antibody |
| MOB-0002MZ | Recombinant Mouse Anti-Human HLA Class II Histocompatibility antigen DR Antibody (clone BB4) | ELISA | Mouse antibody |
| HPAB-1156WJ | Human Anti-HLA-DR Recombinant Antibody (clone HD8) | WB, FC, ADCC, CMCD, Inhib | Human IgG2 |
| HPAB-2054-FY | Human Anti-HLA-DR Recombinant Antibody (clone I-2) | FC | Human IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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