Human Anti-HLA-DR Recombinant Antibody (clone HD8) (CAT#: HPAB-1156WJ)
This product is a human antibody produced from human antibody-producing mouse. This antibody can be used as a preventive or therapeutic agent for diseases caused by an HLA-DR-expressing cell, especially, a therapeutic agent for malignant tumors.
Specific Inquiry
ADCC
Figure 7 A diagram shows the antibody-dependent cellular cytotoxicity (ADCC) of the purified human anti-HLA-DR monoclonal antibody.
Shows the ADCC activities of HD8G1, HD8G2, HD8G2Ser, HD8G4, HD4G1, HD4G2Ser, and HD4G4.
CMCD
Figure 8 A diagram shows the complement-dependent cytotoxicity (CDC) of the purified human anti-HLA-DR monoclonal antibody.
Shows the CDC activities of HD8G1, HD8G2, HD8G2Ser, HD8G4, HD4G1, HD4G2Ser, and HD4G4.
Specifications
- Immunogen
- Human HLA-DR-expressing Cell
- Host Species
- Human
- Type
- Human IgG2
- Specificity
- Human HLA-DR
- Species Reactivity
- Human
- Clone
- HD8
- Applications
- WB, FC, ADCC, CMCD, Inhib
- Related Disease
- Malignant tumors
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HLA-DR antibody has been reported in applications of Western Blot, Flow Cytometry, Antibody-dependent Cell-mediated Cytotoxicity, Complement Mediated Cell Depletion, Inhibition.
Inhib: 5, 50 or 500 µg/kg.
Target
- Alternative Names
- HLA-DR; Human Leukocyte Antigen-DR; L243
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IgG Antibody Products
ScFv Antibody Products
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Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-503 | Recombinant Anti-human HLA-DR Antibody | WB, IHC, FuncS | IgG |
| FN-103CQ | Mouse Anti-HLA-DR Recombinant Antibody (clone L243) | FC, Block | Mouse IgG2a |
| HPAB-0210-WJ | Human Anti-HLA-DR Recombinant Antibody (clone DR4B117) | ELISA, WB | Human IgG1 |
| HPAB-1542-FY | Human Anti-HLA-DR Recombinant Antibody (HPAB-1542-FY) | WB, ELISA | Human IgG1 |
| HPAB-2054-FY | Human Anti-HLA-DR Recombinant Antibody (clone I-2) | FC | Human IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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