AbPlus™ Anti-HMBS Magnetic Beads (VS-0724-YC396) (CAT#: VS-0724-YC396)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-HMBS specific antibody

• Target
• HMBS

• Immunogen
• Recombinant human HMBS fragment derived from E. coli.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

• Alternative Names
• Hydroxymethylbilane Synthase; Porphyria, Acute; Chester Type; Pre-Uroporphyrinogen Synthase; Uroporphyrinogen I Synthase; Porphobilinogen Deaminase; EC 2.5.1.61;

• Gene ID
• 3145

• UniProt ID
• P08397

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