Rabbit Anti-HPX Recombinant Antibody (clone R04-8H4) (CAT#: VS3-XY3386)
It is a recombinant rabbit antibody targeting the HPX (Hemopexin), which binds heme and transports it to the liver for breakdown and iron recovery. It recognizes and binds to human HPX. It has been determined using Western Blot, Immunohistochemistry-Paraffin, Immunoprecipitation, Immunocytochemistry or Immunofluorescence.
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human liver
(Immunohistochemical staining of human liver shows moderate cytoplsmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65318/168888_A_7_4_selected.jpg
(Immunohistochemical staining of human liver shows moderate cytoplsmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65318/168888_A_7_4_selected.jpg
Figure 2 IHC staining of human liver
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68847/168884_A_9_4_selected.jpg
(Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68847/168884_A_9_4_selected.jpg
Figure 3 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows plasma positivity.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16725/37193_A_7_2_selected.jpg
(Immunohistochemical staining of human duodenum shows plasma positivity.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16725/37193_A_7_2_selected.jpg
Figure 4 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16725/37193_A_7_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16725/37193_A_7_4.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16725/37193_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16725/37193_A_9_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16725/37193_A_4_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16725/37193_A_4_6.jpg
Figure 7 RNA cell line category: Cell line enriched (Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110169-HPX
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000110169-HPX
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human HPX
- Species Reactivity
- Human
- Clone
- R04-8H4
- Applications
- WB, IHC-P, ICC, IF, IP
- Related Disease
- Hepatitis E; Acute Chest Syndrome
Product Property
- Clonality
- Monoclonal
- Aggregation
- < 5%
- Format
- Liquid
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% glycerol
- Preservative
- 0.02% sodium azide
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- WB: 1/500-1/1000
IHC: 1/50-1/100
IF: 1/50-1/200
IP: 1/20
Target
- Alternative Names
- HX
- Gene ID
- 3263
- UniProt ID
- P02790
- Long Name
- Hemopexin
- Cellular Localization
- Secreted
- Post Translation Modifications
- Glycosylation at Thr24, Thr29, Thr40, Asn64, Asn187, Asn240, Asn246, and Asn453 (NX_P02790 [NX_P02790-1])
Modification sites at PhosphoSitePlus (P02790)
Glycosylation from GlyConnect HEMO_HUMAN (757)
Glycosylation from GlyGen (P02790) 12 sites, 105 N-linked glycans (5 sites), 9 O-linked glycans (6 sites)
- Protein Refseq
- NP_000604.1
- Function
- Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2465z | Mouse Anti-HPX Recombinant Antibody (clone 31A3) | WB, ELISA, IHC | Mouse IgG1 |
| MOB-0626CT | Recombinant Mouse anti-Human HPX Monoclonal antibody (05) | ELISA, WB | |
| MRO-0731-CN | Rabbit Anti-HPX Recombinant Antibody (clone JU83-33) | WB, IF, IHC, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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