Rabbit Anti-HSPA12A Recombinant Antibody (clone R08-7K2) (CAT#: VS3-XY3389)

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Mouse and Rat HSPA12A

• Species Reactivity
• Human, Mouse, Rat

• Clone
• R08-7K2

• Applications
• WB, IHC-P, ICC, IF, IP

• Related Disease
• Leukoencephalopathy With Vanishing White Matter

• Clonality
• Monoclonal

• Aggregation
• < 5%

• Format
• Liquid

• Buffer
• PBS (pH 7.4), 150 mM NaCl and 50% glycerol

• Preservative
• 0.02% sodium azide

• Storage
• Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

• Shipping
• Ice packs

• Application Notes
• WB: 1/500-1/1000
  IHC: 1/50-1/100
  IF: 1/50-1/200
  IP: 1/20

• Alternative Names
• Heat shock protein family A (Hsp70) member 12A

• Gene ID
• 259217

• UniProt ID
• O43301

• Long Name
• Heat shock protein family A (Hsp70) member 12A

• Cellular Localization
• Cytoplasm, Nucleus

• Post Translation Modifications
• Modification sites at PhosphoSitePlus (O43301)
  Modification sites at neXtProt (NX_O43301)
  Glycosylation from GlyGen (O43301) 2 sites, 1 O-linked glycan (2 sites)

• Protein Refseq
• XP_005269730.1; XP_011537881.1

• Function
• Adapter protein for SORL1, but not SORT1.
  Delays SORL1 internalization and affects SORL1 subcellular localization.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Recommended Dilution Buffer

• MRO-0253YJ
• Reconstitution Buffer PBS

Secondary Antibody

• 2RD-A1473-YJ
• Goat Anti-Rabbit IgG-F(ab')2 Secondary antibody