Mouse Anti-HVR1-6-1 Recombinant Antibody (clone 30F3) (CAT#: FAMAB-0074JF)

Recombinant mouse monoclonal antibody specially binds to HVR1-6-1. This anti-HVR1-6-1 antibody 30F3 can be useful for developing immunological therapy against HCV.

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ELISA

Figure 1 Binding reactivity of 30F3 mAb to the solid-phase corresponding immunogens was inhibited by various competing liquid-phase peptides.

Figure 1 Binding reactivity of 30F3 mAb to the solid-phase corresponding immunogens was inhibited by various competing liquid-phase peptides.

Epitope mapping of 30F3 mAb by competitive ELISA.

Zhou, Y. H., Shimizu, Y. K., & Esumi, M. (2000). Monoclonal antibodies to the hypervariable region 1 of hepatitis C virus capture virus and inhibit virus adsorption to susceptible cells in vitro. Virology, 269(2), 276-283.

WB

Figure 2 Virus capture assays with 30F3 mAb.

Figure 2 Virus capture assays with 30F3 mAb.

The 30F3 mAb were incubated with HCV-6, followed by the addition of anti-mouse IgG.

Zhou, Y. H., Shimizu, Y. K., & Esumi, M. (2000). Monoclonal antibodies to the hypervariable region 1 of hepatitis C virus capture virus and inhibit virus adsorption to susceptible cells in vitro. Virology, 269(2), 276-283.


Specifications

  • Immunogen
  • Full-length of HVR1-6-1
  • Host Species
  • Mouse
  • Type
  • Mouse IgG2b, κ
  • Specificity
  • HVR1-6-1
  • Species Reactivity
  • HCV
  • Clone
  • 30F3
  • Applications
  • WB, ELISA
  • Related Disease
  • Hepatitis C virus

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HVR1-6-1 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • HVR1-6-1; hypervariable region 1 of HCV-6
  • Function
  • Signaling blocking activity

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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