Human Anti-HYOU1 Recombinant Antibody Hexamer (VS-0924-YC132), CDC Enhanced
CAT#: VS-0924-YC132
The product is a human anti-HYOU1 antibody hexamer with enhanced complement-dependent cytotoxicity (CDC) activity. This hexameric IgG1 targets human HYOU1 and includes hexamerization-enhancing mutations. These mutations promote the formation of hexamers, which mediate optimal C1q binding and enhance CDC.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human pancreas
Immunohistochemical staining of human pancreas shows distinct cytoplasmic positivity in exocrine glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49296/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuronal cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49296/109950_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49296/109950_A_9_3.jpg
Normal Tissue
Figure 4 Pancreas
Exocrine glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Pancreatic endocrine cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49296/109950_A_2_3.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49296/109950_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49296/109950_A_9_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (EFO-21)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149428-HYOU1
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Specifications
- Immunogen
- The RPMI8226 cell membrane
- Host Species
- Human
- Type
- Antibody hexamer
- Specificity
- Human HYOU1
- Species Reactivity
- Human
- Molecule Class
- ~ 900 kDa
- Applications
- CDC
- Conjugate
- None
- Related Disease
- Cancer
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% determined as SDS-PAGE and SEC-HPLC
- Aggregation
- <5%
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.
Target
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| HPAB-0007-DJB-S(P) | Mouse Anti-HYOU1 Recombinant Antibody; scFv Fragment (HPAB-0007-DJB-S(P)) | ELISA, Apop | Mouse scFv |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0735-CN | Human Anti-HYOU1 Recombinant Antibody (clone h5F4Ac.2/v17) | WB, ELISA, IP, FC | Humanized IgG3, κ |
| CAT | Product Name | Application | Type |
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| HPAB-0735-CN-S(P) | Human Anti-HYOU1 Recombinant Antibody (clone h5F4Ac.2/v17); scFv Fragment | WB, ELISA, IP, FC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0735-CN-F(E) | Human Anti-HYOU1 Recombinant Antibody (clone h5F4Ac.2/v17); Fab Fragment | WB, ELISA, IP, FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1134-CN | Rabbit Anti-HYOU1 Recombinant Antibody (clone JG39-11) | WB, IHC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP669-YC | Mouse Anti-HYOU1 Recombinant Antibody (clone 3B6.1) | Apop, CDC, FC | Mouse IgM, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP670-YC | Mouse Anti-HYOU1 Recombinant Antibody (clone 6A4.28) | Apop, CDC, FC | Mouse IgM, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP669-YC-S(P) | Mouse Anti-HYOU1 Recombinant Antibody (clone 3B6.1); scFv Fragment | Apop, CDC, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP670-YC-S(P) | Mouse Anti-HYOU1 Recombinant Antibody (clone 6A4.28); scFv Fragment | Apop, CDC, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP671-YC-S(P) | Mouse Anti-HYOU1 Recombinant Antibody (clone 9A6.2); scFv Fragment | Apop, CDC, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP669-YC-F(E) | Mouse Anti-HYOU1 Recombinant Antibody (clone 3B6.1); Fab Fragment | Apop, CDC, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP670-YC-F(E) | Mouse Anti-HYOU1 Recombinant Antibody (clone 6A4.28); Fab Fragment | Apop, CDC, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-AP671-YC-F(E) | Mouse Anti-HYOU1 Recombinant Antibody (clone 9A6.2); Fab Fragment | Apop, CDC, FC | Mouse Fab |
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| VS-0424-XY138 | AbPlus™ Anti-HYOU1 Magnetic Beads (h5F4Ac.2/v17) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC131 | Mouse Anti-HYOU1 Recombinant Antibody Hexamer (VS-0924-YC131), CDC Enhanced | Apop, CDC, FC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3364 | Anti-HYOU1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
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| VS-0525-XY3365 | Anti-Mouse HYOU1 Immunohistochemistry Kit | IHC |
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