Human Anti-IAV H5N1 HA Recombinant Antibody (clone VH 3-33) (CAT#: FAMAB-0012JF)
Recombinant mouse monoclonal antibody specially binds to H1N1 HA head S. This anti-HA head antibody VH 3-33 can be widely used in the selection of diseased lung.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
ELISA
Figure 3 Measurement of IgG1 antibody titers by ELISA in HA1-Fc- and HA1-Fdc-vaccianted mouse sera.
PBS was used as the negative control.
Du, L., Zhang, X., Zhou, J., Chen, M., He, W., Zhang, H. Y., ... & Cai, L. (2011). A recombinant vaccine of H5N1 HA1 fused with foldon and human IgG Fc induced complete cross-clade protection against divergent H5N1 viruses. PloS one, 6(1), e16555.
IHC
Figure 4 Evaluation of histopathological changes in lung tissues of H5N1 virus-challenged mice.
Lung tissues from mice injected with PBS and those of uninfected mice were used as negative and normal controls, respectively.
Du, L., Zhang, X., Zhou, J., Chen, M., He, W., Zhang, H. Y., ... & Cai, L. (2011). A recombinant vaccine of H5N1 HA1 fused with foldon and human IgG Fc induced complete cross-clade protection against divergent H5N1 viruses. PloS one, 6(1), e16555.
FC
Figure 5 Flow cytometry-based EC50 measurements with mean fluorescence intensity (MFI) for the IgGs binding to cell surface-expressed H5N1 VN/04 HA trimers on 293 T cells.
The IgGs were reformatted from the selected anti-HA trimer scFvs as shown.
Chen, C., Chiu, Y. K., Yu, C. M., Lee, C. C., Tung, C. P., Tsou, Y. L., ... & Yang, A. S. (2017). High throughput discovery of influenza virus neutralizing antibodies from phage-displayed synthetic antibody libraries. Scientific reports, 7(1), 1-17.
Specifications
- Immunogen
- Influenza vaccine
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- H1N1 HA head S
- Species Reactivity
- H1N1
- Clone
- VH 3-33
- Applications
- WB, ELISA, Neut, IHC, FC
- Related Disease
- Influenza viruses Infection
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IAV H5N1 HA antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Neutralization, Flow Cytometry.
Target
- Alternative Names
- Influenza A Virus H1N1 HA; Influenza A Virus H1N1 haemagglutinin
- Gene ID
- 23308115
- UniProt ID
- C3W627
- Function
- Neutralization
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1119CQ | Recombinant Mouse Anti-IAV H5N1 HA Antibody (MRO-1119CQ) | ELISA | Mouse antibody |
| MRO-1120CQ | Recombinant Mouse Anti-IAV H5N1 HA Antibody (MRO-1120CQ) | ELISA | Mouse antibody |
| MRO-1121CQ | Recombinant Mouse Anti-IAV H5N1 HA Antibody (MRO-1121CQ) | ELISA | Mouse antibody |
| FAMAB-0076WJ | Human Anti-IAV H5N1 HA Recombinant Antibody (clone 3C11) | Neut, ELISA | Human IgG |
| PABJ-0178 | Human Anti-IAV H5N1 HA Recombinant Antibody (clone AVFluIgG01) | Neut | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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