AbPlus™ Anti-ICAM3 Magnetic Beads (VS-0724-YC892) (CAT#: VS-0724-YC892)
The AbPlus Anti-ICAM3 Magnetic Beads (VS-0724-YC892) is an innovative affinity resin which is bound with anti-ICAM3 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of ICAM3 protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nuclear membrane & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49820/if_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nuclear membrane & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49820/if_selected.jpg

Figure 2 IHC staining of human bone marrow
(High expression. RNA expression: 206.5 nTPM.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_5_4_val_selected.jpg
(High expression. RNA expression: 206.5 nTPM.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_5_4_val_selected.jpg

Figure 3 IHC staining of human cerebral cortex
(Low expression. RNA expression: 6.4 nTPM.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_7_5_val_selected.jpg
(Low expression. RNA expression: 6.4 nTPM.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_7_5_val_selected.jpg

Figure 4 Colon
(Endothelial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_9_3.jpg
(Endothelial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_9_3.jpg

Figure 5 Kidney
(Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_5.jpg
(Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_5.jpg

Figure 6 Lymph node
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_8.jpg
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_8.jpg

Figure 7 RNA cell line category: Cell line enhanced (Karpas-707, NB-4, RPMI-8226, U-266/84, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076662-ICAM3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076662-ICAM3
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-ICAM3 specific antibody
- Target
- ICAM3
- Immunogen
- Recombinant human ICAM3/CD50, aa 1-485.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
- Alternative Names
- Intercellular Adhesion Molecule 3
- Gene ID
- 3385
- UniProt ID
- P32942
Downloads
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Extracellular Vesicle (EV) Antibody Products
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-534-F(E) | Recombinant Anti-human ICAM3 Antibody Fab Fragment | Neut, IF, FuncS | Fab |
MHH-534-F(E) | Recombinant Human Anti-human ICAM3 Antibody Fab Fragment | WB, ELISA, IHC, FuncS | Fab |
HPAB-1602WJ-F(E) | Mouse Anti-ICAM3 Recombinant Antibody; Fab Fragment (clone ICR-8.1) | ELISA, WB, FC | Mouse Fab |
HPAB-1603WJ-F(E) | Human Anti-ICAM3 Recombinant Antibody; Fab Fragment (clone huICR-8.1) | ELISA, WB, FC | Human Fab |
HPAB-1604WJ-F(E) | Mouse Anti-ICAM3 Recombinant Antibody; Fab Fragment (clone ICR-1.1) | ELISA, WB, FC | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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