AbPlus™ Anti-ICAM3 Magnetic Beads (VS-0724-YC892)
CAT#: VS-0724-YC892
The AbPlus Anti-ICAM3 Magnetic Beads (VS-0724-YC892) is an innovative affinity resin which is bound with anti-ICAM3 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of ICAM3 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nuclear membrane & mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49820/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human bone marrow
High expression. RNA expression: 206.5 nTPM.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_5_4_val_selected.jpg
Normal Tissue
Figure 3 IHC staining of human cerebral cortex
Low expression. RNA expression: 6.4 nTPM.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_7_5_val_selected.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_9_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_5.jpg
Normal Tissue
Figure 6 Lymph node
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (Karpas-707, NB-4, RPMI-8226, U-266/84, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076662-ICAM3
❮
❯
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-ICAM3 specific antibody
- Target
- ICAM3
- Immunogen
- Recombinant human ICAM3/CD50, aa 1-485.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
- Alternative Names
- Intercellular Adhesion Molecule 3
- Gene ID
- 3385
- UniProt ID
- P32942
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Datasheet
MSDS
COA
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