Recombinant Human Anti-human ICAM3 Antibody (CAT#: MHH-534)
Recombinant Human Antibody is closely related to binding with Human ICAM3, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-ICAM3 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-ICAM3 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nuclear membrane & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49820/if_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nuclear membrane & mitochondria.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/49820/if_selected.jpg
Figure 2 IHC staining of human bone marrow
(High expression. RNA expression: 206.5 nTPM.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_5_4_val_selected.jpg
(High expression. RNA expression: 206.5 nTPM.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_5_4_val_selected.jpg
Figure 3 IHC staining of human cerebral cortex
(Low expression. RNA expression: 6.4 nTPM.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_7_5_val_selected.jpg
(Low expression. RNA expression: 6.4 nTPM.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_7_5_val_selected.jpg
Figure 4 Colon
(Endothelial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_9_3.jpg
(Endothelial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_9_3.jpg
Figure 5 Kidney
(Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_5.jpg
(Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_5.jpg
Figure 6 Lymph node
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_8.jpg
(Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_8.jpg
Figure 7 RNA cell line category: Cell line enhanced (Karpas-707, NB-4, RPMI-8226, U-266/84, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076662-ICAM3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076662-ICAM3
Specifications
- Immunogen
- Human intercellular adhesion molecule 3
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human intercellular adhesion molecule 3
- Species Reactivity
- Human
- Applications
- Used for immunoassaytechniques such as: Immunofluorescence; Enzyme-linked Immunosorbent Assay; Functional Study
Product Property
- Purity
- >95% (SDS-PAGE)
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Target
- Alternative Names
- ICAM3; intercellular adhesion molecule 3; CD50; CDW50; ICAM-R; ICAM-3; intercellular adhesion molecule-3
- Gene ID
- 3385
- UniProt ID
- A0A024R7C1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-534 | Recombinant Anti-human ICAM3 Antibody | WB, FC, FuncS | IgG |
| MOB-0165CT | Recombinant Mouse anti-Human ICAM3 Monoclonal antibody (EML427) | IHC-P, WB | |
| HPAB-1602WJ | Mouse Anti-ICAM3 Recombinant Antibody (clone ICR-8.1) | ELISA, WB, FC | Mouse IgG1, κ |
| ZG-1011F | Mouse Anti-ICAM3 Recombinant Antibody (clone BH10) | ELISA, FC, IHC-Fr, ICC, IP, WB | Mouse IgG1, κ |
| VS2-QX13 | Mouse Anti-ICAM3 Recombinant Antibody (clone BRIC 79) | FuncS | Mouse IgG2a, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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