Recombinant Human Anti-human ICAM3 Antibody Fab Fragment

Name: Recombinant Human Anti-human ICAM3 Antibody Fab Fragment
SKU: MHH-534-F(E)
Rating: 5 (1 reviews)

CAT#: MHH-534-F(E)

Recombinant Human Antibody Fab Fragment is capable of specifically reacting with Human ICAM3, expressed in HEK 293 cells.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line MCF7

Immunofluorescent staining of human cell line MCF7 shows localization to nucleoplasm, nuclear membrane & mitochondria.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49820/if_selected.jpg

Normal Tissue Figure 2 IHC staining of human bone marrow

High expression. RNA expression: 206.5 nTPM.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_5_4_val_selected.jpg

Normal Tissue Figure 3 IHC staining of human cerebral cortex

Low expression. RNA expression: 6.4 nTPM.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_B_7_5_val_selected.jpg

Normal Tissue Figure 4 Colon

Endothelial cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_9_3.jpg

Normal Tissue Figure 5 Kidney

Cells in tubules
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_5.jpg

Normal Tissue Figure 6 Lymph node

Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/2498/6124_A_8_8.jpg

RNA Expression Figure 7 RNA cell line category: Cell line enhanced (Karpas-707, NB-4, RPMI-8226, U-266/84, U-937)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000076662-ICAM3

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Specifications

Immunogen
Human intercellular adhesion molecule 3

Host Species
Human

Derivation
Human

Type
Fab

Antibody Isotype
Fab Fragment based on human IgG1

Specificity
Tested positive against native Human intercellular adhesion molecule 3

Species Reactivity
Human

Applications
Products can be used for: Western blot; Enzyme-linked Immunosorbent Assay; Immunohistochemistry; Functional Study

Product Property

Purity
Purity>95% by SDS-PAGE

Storage
Store at – 20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.

Target

Alternative Names
ICAM3; intercellular adhesion molecule 3; CD50; CDW50; ICAM-R; ICAM-3; intercellular adhesion molecule-3

Gene ID
3385

UniProt ID
A0A024R7C1

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - MHH-534-F(E).pdf

MSDS

MSDS - MHH-534-F(E).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Protocol & Troubleshooting

Immunohistochemistry (IHC)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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