This recombinant monoclonal antibody to human IDE is a mouse monoclonal antibody that can be used for applications: ELISA.
Figure 1 Sensorgram traces for the interaction of Fab(IDE) to immobilized IDE.
Black lines show experimental data, and red lines display the best fit of the global 1:1 Langmuir model, which resulted in association [ka = 2.18 ± 0.02 (×105) M-1s-1] and dissociation (kd = 5.87 ± 0.05 (×10-3) s-1] rate constants and the derived equilibrium constant (KD = 3.72 ± 0.03 nM).
McCord, L. A., Liang, W. G., Dowdell, E., Kalas, V., Hoey, R. J., Koide, A., ... & Tang, W. J. (2013). Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme. Proceedings of the National Academy of Sciences, 110(34), 13827-13832.
Figure 2 Fab(IDE) does not affect IDE catalytic activity.
Catalytic activity of IDE in the absence and presence of the equal molar Fab(IDE) was measured at varying concentrations of Substrate V. Data points represent mean ± SD (n = 3). A sigmoidal curve (Hill equation with Hill coefficient = ∼2) was fit to each data set.
McCord, L. A., Liang, W. G., Dowdell, E., Kalas, V., Hoey, R. J., Koide, A., ... & Tang, W. J. (2013). Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme. Proceedings of the National Academy of Sciences, 110(34), 13827-13832.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-535-F(E) | Recombinant Anti-human IDE Antibody Fab Fragment | Neut, WB, FuncS | Fab |
MHH-535-F(E) | Recombinant Human Anti-human IDE Antibody Fab Fragment | ELISA, RIA, FuncS | Fab |
PFBL-589 | Mouse Anti-IDE Recombinant Antibody (clone YC113); Fab Fragment | WB, FuncS | Mouse Fab |
PFBS-0055 | Mouse Anti-IDE Recombinant Antibody (Clone Fab(IDE)); Fab Fragment | ELISA, FuncS | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-535-S(P) | Recombinant Anti-human IDE Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
MHH-535-S(P) | Recombinant Human Anti-human IDE Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
PSBL-589 | Mouse Anti-IDE Recombinant Antibody (clone YC113); scFv Fragment | WB, FuncS | Mouse scFv |
PSBS-0055 | Mouse Anti-IDE Recombinant Antibody (Clone Fab(IDE)); scFv Fragment | ELISA, FuncS | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MHH-535 | Recombinant Human Anti-human IDE Antibody | WB, FC, FuncS | IgG |
PABL-594 | Mouse Anti-IDE Recombinant Antibody (clone YC112) | WB, FuncS | Mouse IgG |
MRO-0844-CN | Rabbit Anti-IDE Recombinant Antibody (clone JJ0949) | WB, IHC | Rabbit IgG |
VS3-CJ656 | Mouse Anti-IDE Recombinant Antibody (VS3-CJ656) | WB, IHC | Mouse IgG |
VS3-FY2017 | Rabbit Anti-IDE Recombinant Antibody (clone R04-4E8) | WB, IF | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-110 | Recombinant Human Anti-IDE Antibody | WB, Neut, FuncS | IgG |
PABX-110-S (P) | Recombinant Human Anti-IDE Antibody scFv Fragment | WB, Neut, FuncS | scFv |
PABX-110-F (E) | Recombinant Human Anti-IDE Antibody Fab Fragment | WB, Neut, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1732 | Rabbit Anti-IDE Recombinant Antibody (clone DS1732AB) | WB, ICC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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