Rabbit Anti-IGFBP6 Recombinant Antibody (clone R02-6G2) (CAT#: VS3-FY1746)
This anti-IGFBP6 antibody detected positive in western blot analysis of IGFBP6 in K562, Hela lysates. The recombinant monoclonal antibody demonstrates specificity in binding to human IGFBP6 protein, a calculated weight of 25 kDa.
Specific Inquiry
WB
Figure 1 Anti-IGFBP6 Antibody (VS3-FY1746) in WB.
The IGFBP6 expression in K562, Hela lysates were detected using the anti-IGFBP6 by western blot assay.
Specifications
- Immunogen
- Recombinant human IGFBP6 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human IGFBP6
- Species Reactivity
- Human
- Clone
- R02-6G2
- Applications
- Western Blot
- MW
- The calculated weight of the target protein is approximately 25 kDa, while the observed molecular weight stands at 35 kDa.
- Related Disease
- Insulin-Like Growth Factor I and Exfoliative Ichthyosis
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Target
- Alternative Names
- Insulin Like Growth Factor Binding Protein 6
- Gene ID
- 3489
- UniProt ID
- P24592
- Cellular Localization
- Secreted
- Post Translation Modifications
- O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylated on one site only in the region AA 143-168 in cerebrospinal fluid.
- Protein Refseq
- XP_047284742.1; XP_054227929.1; NP_002169.1
- Function
- IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2257MZ | Recombinant Mouse Anti-Human IGFBP6 Antibody | ELISA, WB | Mouse antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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