Recombinant Anti-IL17F Eliminating Antibody, pH-Sensitive (VS-0625-YC169)
CAT#: VS-0625-YC169
The anti-IL17F eliminating antibody is an engineered pH-sensitive antibody against human, cynomolgus, mouse and rat IL17F. IL17F, similar to IL17, stimulates cytokine production and inhibits endothelial angiogenesis. The antibody has a novel IL17F-sweeping activity in vivo, which selectively eliminatesthe soluble IL17F from plasma. Compared to conventional antibody, the mAb exerted in vivo efficacy by simultaneously engineering both pH-dependent antigen binding, to mimic the pH-dependent receptor-ligand binding of such endocytic receptors, and increased FcRn binding affinity at neutral pH, to mimic the cell-bound form of the receptors.
Specifications
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human, Cynomolgus, Mouse and Rat IL17F
- Species Reactivity
- Human, Cynomolgus, Mouse, Rat
- Applications
- Antigen-Sweeping In Vivo.
Product Property
- Purification
- Protein A/G purified
- Purity
- >95%
- Format
- Liquid
- Buffer
- PBS only
- Preservative
- None
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-0625-YC169. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Related Diseases
Inflammatory Bowel Diseases
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "IL17F"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-033ZJ | Anti-Human IL-17F Recombinant Antibody | ELISA, IP | |
| TAB-033ZJ-S(P) | Anti-Human IL-17F Recombinant Antibody scFv Fragment | ELISA, IP | |
| TAB-033ZJ-F(E) | Anti-Human IL-17F Recombinant Antibody Fab Fragment | ELISA, IP |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-279CQ | Human Anti-IL17F Recombinant Antibody (TAB-279CQ) | ELISA, WB, IP | Human IgG |
| TAB-279CQ-S(P) | Human Anti-IL17F Recombinant Antibody; scFv Fragment (TAB-279CQ-S(P)) | ELISA, WB, IP | Human scFv |
| TAB-279CQ-F(E) | Human Anti-IL17F Recombinant Antibody; Fab Fragment (TAB-279CQ-F(E)) | ELISA, WB, IP | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1227CQ | Mouse Anti-IL17F Recombinant Antibody (clone CBL653) | Neut | Mouse IgG1 |
| NEUT-1228CQ | Rat Anti-IL17F Recombinant Antibody (NEUT-1228CQ) | FC, FuncS, Neut, IF | Rat IgG1, κ |
| NEUT-1229CQ | Rat Anti-Il17f Recombinant Antibody (VMC191) | FuncS, Neut | Rat IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4611 | Rabbit Anti-IL17F Recombinant Antibody (clone TH124DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0281-CN-S(P) | Human Anti-IL17F Recombinant Antibody; scFv Fragment (HPAB-0281-CN-S(P)) | ELISA, Neut | Humanized scFv |
| HPAB-0282-CN-S(P) | Mouse Anti-IL17F Recombinant Antibody; scFv Fragment (HPAB-0282-CN-S(P)) | ELISA, Neut | Mouse scFv |
| HPAB-1222-FY-F(E) | Human Anti-IL17F Recombinant Antibody; Fab Fragment (HPAB-1222-FY-F(E)) | Block | Human Fab |
| HPAB-1223-FY-F(E) | Human Anti-IL17F Recombinant Antibody; Fab Fragment (HPAB-1223-FY-F(E)) | Block | Human Fab |
| HPAB-1227-FY-F(E) | Human Anti-IL17F Recombinant Antibody; Fab Fragment (HPAB-1227-FY-F(E)) | Block | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1222-FY | Human Anti-IL17F Recombinant Antibody (HPAB-1222-FY) | Inhib, WB, ELISA, IF | Human IgG1 |
| HPAB-1223-FY | Human Anti-IL17F Recombinant Antibody (HPAB-1223-FY) | WB, ELISA, FC, IHC | Human IgG1 |
| HPAB-1224-FY | Human Anti-IL17F Recombinant Antibody (HPAB-1224-FY) | Inhib, WB, IHC, ELISA | Human IgG4 |
| HPAB-1225-FY | Human Anti-IL17F Recombinant Antibody (HPAB-1225-FY) | Block | Human IgG1 |
| HPAB-1226-FY | Human Anti-IL17F Recombinant Antibody (HPAB-1226-FY) | Block | Human IgG3 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0827-WJ-F(E) | Human Anti-IL17F Recombinant Antibody; Fab Fragment (HPAB-0827-WJ-F(E)) | ELISA, WB | Humanized Fab |
| HPAB-0828-WJ-F(E) | Human Anti-IL17F Recombinant Antibody; Fab Fragment (HPAB-0828-WJ-F(E)) | ELISA, WB | Humanized Fab |
| HPAB-0829-WJ-F(E) | Human Anti-IL17F Recombinant Antibody; Fab Fragment (HPAB-0829-WJ-F(E)) | ELISA, WB | Humanized Fab |
| HPAB-0968WJ-F(E) | Mouse Anti-IL17F Recombinant Antibody; Fab Fragment (HPAB-0968WJ-F(E)) | ELISA, Neut | Mouse Fab |
| HPAB-0969WJ-F(E) | Mouse Anti-IL17F Recombinant Antibody; Fab Fragment (HPAB-0969WJ-F(E)) | ELISA, Neut | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY148 | AbPlus™ Anti-IL17F Magnetic Beads (VS-0424-XY148) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3495 | Anti-IL17F Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: WB, IP, IF, FuncS, FC, Neut, ELISA
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC
Application: WB, IHC, FC, Cyt, ELISA
Application: Neut, ELISA, Inhib, ICC, WB
Application: WB, ELISA, FuncS, IB, FC, SPR, Apop
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: ELISA, FC, IF, IHC, WB
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
