Mouse Anti-KIF7 Recombinant Antibody (VS3-FY2751)
CAT#: VS3-FY2751
The anti-KIF7 antibody is specifically created to bind human KIF7 protein. It exhibits cross-reactivity with mouse and rat. This monoclonal antibody proves valuable in disease research related to Al-Gazali-Bakalinova Syndrome and Acrocallosal Syndrome.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Kinesin family member 7 of human, mouse and rat origins
- Species Reactivity
- Human, Mouse, Rat
- Applications
- IHC, ICC
- Conjugate
- Unconjugated, FITC
- Related Disease
- Al-Gazali-Bakalinova Syndrome and Acrocallosal Syndrome
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Immunohistochemistry: 1/50-1/100
Immunocytochemistry: 1/50-1/200
Target
- Alternative Names
- Kinesin Family Member 7; Kinesin-Like Protein KIF7; EQYK340; JBTS12; UNQ340; ACLS; AGBK; HLS2
- Gene ID
- 374654
- UniProt ID
- Q2M1P5
- Sequence Similarities
- Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF27 subfamily.
- Cellular Localization
- Cell projection, cilium
Cytoplasm, cytoskeleton, cilium basal body
- Post Translation Modifications
- Polyubiquitinated by UBR3.
Ubiquitination at Lys1208 and Lys1278
Modification sites at PhosphoSitePlus
- Protein Refseq
- XP_011519833.1; XP_047288433.1; XP_047288434.1; XP_047288435.1; XP_047288436.1
- Function
- Essential for hedgehog signaling regulation: acts both as a negative and positive regulator of sonic hedgehog (Shh) and Indian hedgehog (Ihh) pathways, acting downstream of SMO, through both SUFU-dependent and -independent mechanisms (PubMed:21633164).
Involved in the regulation of microtubular dynamics.
Required for proper organization of the ciliary tip and control of ciliary localization of SUFU-GLI2 complexes (By similarity).
Required for localization of GLI3 to cilia in response to Shh.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "KIF7"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-WK1024 | Mouse Anti-KIF7 Recombinant Antibody (VS3-WK1024) | WB | Mouse IgG |
| VS3-WK1401 | Mouse Anti-KIF7 Recombinant Antibody (clone 3F8) | IHC | Mouse IgG1 |
| VS4-WK267 | Mouse Anti-KIF7 Recombinant Antibody (VS4-WK267) | ELISA, IHC | Mouse IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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