Anti-KLK2 (clone W24V311) Recombinant Antibody Coupled Liposome (VS-1024-FY300)
CAT#: VS-1024-FY300
Anti-KLK2 antibody conjugated liposomes have the potential to enhance targeted drug delivery specifically to prostate cancer cells, minimizing off-target effects and improving therapeutic efficacy. This targeted approach may facilitate more effective treatment regimens and improve patient outcomes by overcoming resistance to conventional therapies.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human prostate
Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/764/2093_A_1_5_selected.jpg
Normal Tissue
Figure 2 Prostate
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/764/2093_A_3_5.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (BEWO, NB-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167751-KLK2
❮
❯
More Infomation
Specifications
- Potential Clinical Applications
- Prostate cancer
Product Composition
- Clone
- W24V311
- Antibody Type
- IgG
- Antibody Host
- Mouse
- Antibody Reactivity
- Human
- Antibody Description
- This is a recombinant mouse monoclonal antibody that was specifically developed to bind to KLK2. Engineered through sophisticated molecular cloning techniques, this antibody showcases a high degree of specificity for KLK2, a serine protease linked to various physiological processes and potential disease states. Its ability to selectively interact with KLK2 makes it an essential reagent in the study of prostate cancer and other conditions where KLK2 plays a pivotal role.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- KLK2
- Introduction
- This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk.
- Alternative Names
- hK2; hGK-1; KLK2A2; kallikrein-2; glandular kallikrein 2 glandular kallikrein-1 kallikrein 2, prostatic tissue kallikrein-2
- Full Name
- Kallikrein Related Peptidase 2
- Gene ID
- 3817
- UniProt ID
- P20151
- Sequence Similarities
- Belongs to the peptidase S1 family.
- Post Translation Modifications
- Glycosylation at Asn102 (NX_P20151 [NX_P20151-1])
Modification sites at PhosphoSitePlus (P20151)
Glycosylation from GlyGen (P20151) 1 site
- Protein Refseq
- NP_001002231.1; NP_001243009.1; NP_005542.1
- Function
- Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS-1024-FY300. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "KLK2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0622CL | Mouse Anti-KLK2 Recombinant Antibody (TAB-0622CL) | FuncS, IF | Mouse IgG |
| TAB-0622CL-S(P) | Mouse Anti-KLK2 Recombinant Antibody; scFv Fragment (TAB-0622CL-S(P)) | ELISA | Mouse scFv |
| TAB-0622CL-F(E) | Mouse Anti-KLK2 Recombinant Antibody; Fab Fragment (TAB-0622CL-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1644CQ | Recombinant Mouse Anti-KLK2 Antibody (CBL629) | WB, IP, Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1961 | Hi-Affi™ Recombinant Rabbit Anti-KLK2 Monoclonal Antibody (DS1961AB) | WB, ICC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0246-CN | Human Anti-KLK2 Recombinant Antibody (HPAB-0246-CN) | ELISA | Humanized IgG1, κ |
| VS1-YJ113 | Mouse Anti-KLK2 Recombinant Antibody (clone 6B7) | ELISA, IF, ICC, IHC-P | Mouse IgG1 |
| VS1-YJ114 | Mouse Anti-KLK2 Recombinant Antibody (clone 6B7), HRP | ELISA, IF, ICC, IHC-P | Mouse IgG1 |
| VS1-YJ198 | Mouse Anti-KLK2 Recombinant Antibody (clone 6B7), BSA/Azide Free | ELISA, IF, ICC, IHC-P | Mouse IgG1 |
| VS13-YC627 | Rabbit Anti-KLK2 Recombinant Antibody (VS13-YC627) | WB, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0246-CN-S(P) | Human Anti-KLK2 Recombinant Antibody; scFv Fragment (HPAB-0246-CN-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0246-CN-F(E) | Human Anti-KLK2 Recombinant Antibody; Fab Fragment (HPAB-0246-CN-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1197 | Anti-KLK2 Immunohistochemistry Kit | IHC |
See Our Custom Production in Action
Popular Products
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, WB
-YJ5.png)
Application: WB, ELISA, FC, IHC, IP
Application: ELISA, IHC, FC, IP, IF, Inhib
-2.png)
Application: ELISA
Application: WB, FC, IF, Inhib, ELISA, IHC
Application: ELISA, FC
Application: ELISA, FC, FuncS
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
