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    Rabbit Anti-LETM1 Antibody (VS-0924-YC69) - Cancer Stem Cell Marker (CAT#: VS-0924-YC69)

    This product is an anti-LETM1 antibody (VS-0924-YC69). It specifically targets the human LETM1 protein, which is a marker for cancer stem cells (CSCs). This antibody is suitable for detecting LETM1 in CSC tissues or cells using Immunohistochemistry (1:200-1:500), Immunofluorescence (0.5-2 µg/mL), and Western blot (0.1-0.5 µg/mL).

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Fc Engineering:

    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to mitochondria.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11029/if_selected.jpg
    Figure 2 IHC staining of human kidney
    Figure 2 IHC staining of human kidney
    (Immunohistochemical staining of human kidney shows strong granular cytoplasmic positivity in cells in tubules.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11029/ihc_selected.jpg
    Figure 3 IHC staining of human colon
    Figure 3 IHC staining of human colon
    (Immunohistochemical staining of human colon shows strong cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11100/ihc_selected.jpg
    Normal Tissue
    Figure 4 Cerebral cortex
    Figure 4 Cerebral cortex
    (Glial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Neuropil
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11029/27624_B_8_5.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Hepatocytes
    Staining: Low
    Intensity: Weak
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11029/27588_A_8_4.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Leydig cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Spermatogonia cells
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11029/27588_A_6_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/11029/27588_A_7_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168924-LETM1

    Specifications

    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human LETM1
    • Species Reactivity
    • Human
    • Applications
    • IHC, WB, IF
    • Related Disease
    • Disease variant, Neurodegeneration

    Product Property

    • Clonality
    • Polyclonal
    • Purification
    • Affinity purified using the PrEST antigen as affinity ligand
    • Concentration
    • 0.2 mg/mL
    • Buffer
    • PBS, pH 7.2, with 40% glycerol
    • Preservative
    • 0.02% Sodium azide
    • Storage
    • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Applications

    • Application Notes
    • Immunohistochemistry (IHC): 1/200-1/500
      Western Blot (WB): 0.1-0.5 µg/mL
      Immunofluorescence (IF): 0.5-2 µg/mL

    Target

    • Alternative Names
    • KHE; Mdm38; CONDMIM; SLC55A1
    • Long Name
    • Leucine zipper-EF-hand containing transmembrane protein 1
    • Cellular Localization
    • #Membrane
      #Mitochondrion
      #Mitochondrion inner membrane
    • Post Translation Modifications
    • #Acetylation
      #Phosphoprotein
    • Function
    • #Antiport
      #Calcium transport
      #Ion transport
      #Potassium transport
      #Transport

    Recommended Products

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    Secondary Antibody

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "LETM1"

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    IgG Antibody Products IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
    CAT Product Name Application Type
    MOB-1085CT Recombinant Mouse anti-Human LETM1 Monoclonal antibody (EML505) ICC/IF, IHC-P, WB

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    For Research Use Only. Not For Clinical Use.

    For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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