Mouse Anti-LIN28B Recombinant Antibody (VS3-FY2788) (CAT#: VS3-FY2788)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human and Mouse LIN28B

• Species Reactivity
• Human, Mouse

• Applications
• Western Blot

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 27.1 kDa.

• Related Disease
• Neuroblastoma; Acrocephalopolysyndactyly Type Iii

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/2000

• Alternative Names
• CSDD2

• Gene ID
• 389421

• UniProt ID
• Q6ZN17

• Cellular Localization
• Nucleus, Nucleolus, Cytoplasm

• Post Translation Modifications
• Modification sites at PhosphoSitePlus (Q6ZN17)
  Modification sites at neXtProt (NX_Q6ZN17)
  Glycosylation from GlyGen (Q6ZN17) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• XP_054211391.1

• Function
• Suppressor of microRNA (miRNA) biogenesis, including that of let-7 and possibly of miR107, miR-143 and miR-200c.
  Binds primary let-7 transcripts (pri-let-7), including pri-let-7g and pri-let-7a-1, and sequester them in the nucleolus, away from the microprocessor complex, hence preventing their processing into mature miRNA (PubMed:22118463).
  Does not act on pri-miR21.

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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