Mouse Anti-LIN28B Recombinant Antibody (VS3-FY2788)
CAT#: VS3-FY2788
This mouse anti-LIN28B recombinant monoclonal antibody is specifically targeting the human, mouse LIN28B protein, a calculated molecular weight of the protein is about 27.1 kDa. This monoclonal antibody proves valuable in disease research related to Neuroblastoma, Acrocephalopolysyndactyly Type Iii.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human and Mouse LIN28B
- Species Reactivity
- Human, Mouse
- Applications
- Western Blot
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 27.1 kDa.
- Related Disease
- Neuroblastoma; Acrocephalopolysyndactyly Type Iii
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Target
- Alternative Names
- CSDD2
- Gene ID
- 389421
- UniProt ID
- Q6ZN17
- Cellular Localization
- Nucleus, Nucleolus, Cytoplasm
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q6ZN17)
Modification sites at neXtProt (NX_Q6ZN17)
Glycosylation from GlyGen (Q6ZN17) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_054211391.1
- Function
- Suppressor of microRNA (miRNA) biogenesis, including that of let-7 and possibly of miR107, miR-143 and miR-200c.
Binds primary let-7 transcripts (pri-let-7), including pri-let-7g and pri-let-7a-1, and sequester them in the nucleolus, away from the microprocessor complex, hence preventing their processing into mature miRNA (PubMed:22118463).
Does not act on pri-miR21.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "LIN28B"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0927-CN | Recombinant Mouse Anti-LIN28B Monoclonal Antibody (A2-4-5) | WB, IF, IHC | Mouse IgG2a |
| VS3-QX692 | Mouse Anti-LIN28B Recombinant Antibody (clone A2-4-5) | WB, ICC, IHC | Mouse IgG2a |
| VS3-WK1043 | Mouse Anti-LIN28B Recombinant Antibody (VS3-WK1043) | WB | Mouse IgG1, κ |
| VS3-XY3417 | Rabbit Anti-LIN28B Recombinant Antibody (clone R05-7F1) | WB, ICC, IF, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4040 | Anti-LIN28B Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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