Rabbit Anti-LLGL1 Recombinant Antibody (clone R05-0B8) (CAT#: VS3-FY2024)
The anti-LLGL1 antibody detected positive in western blot analysis of LLGL1 in A549, U2OS lysates. The recombinant monoclonal antibody demonstrated a greater affinity with human LLGL1. It is suitable for use in a variety of assays, including WB, IP.
Specific Inquiry
WB
Figure 1 Anti-LLGL1 Antibody (VS3-FY2024) in WB.
The LLGL1 expression in A549, U2OS lysates were detected using the anti-LLGL1 by western blot assay.
Specifications
- Immunogen
- Recombinant human LLGL1 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human LLGL1
- Species Reactivity
- Human
- Clone
- R05-0B8
- Applications
- Western Blot, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 115 kDa, while the observed molecular weight stands at 115 kDa.
- Related Disease
- Smith-Magenis Syndrome and Alzheimer Disease 12
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- LLGL1; DLG4; HUGL; HUGL-1; HUGL1; LLGL; Lgl1; Mgl1; scribble cell polarity complex component; LLGL scribble cell polarity complex component 1
- Gene ID
- 3996
- UniProt ID
- Q15334
- Sequence Similarities
- Belongs to the WD repeat L(2)GL family.
- Cellular Localization
- Cell projection, Cytoplasm, Cytoskeleton, Endosome, Golgi apparatus, Membrane
- Post Translation Modifications
- Phosphorylated at least at Ser-663 by PRKCI. (Q15334-L2GL1_HUMAN)
Ubiquitination at Lys19, Lys27, Lys293, Lys502, and Lys780 (NX_Q15334 [NX_Q15334-1])
Modification sites at PhosphoSitePlus (Q15334)
Glycosylation from GlyGen (Q15334) 1 site, 2 O-linked glycans (1 site)
- Protein Refseq
- XP_011522151.1; XP_011522152.1; XP_011522153.1; XP_011522154.1; XP_011522155.1
- Function
- Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "LLGL1"
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2064 | Hi-Affi™ Recombinant Rabbit Anti-LLGL1 Monoclonal Antibody (DS2064AB) | ELISA, WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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