Rabbit Anti-MAP2K2 Recombinant Antibody (VS13-YC688) (CAT#: VS13-YC688)
The Rabbit Anti-MAP2K2 Recombinant Antibody is specific for human, mouse and rat MAP2K2. MAP2K2, a kinase family member, phosphorylates MAPK1/ERK2 and MAPK2/ERK3, involved in signal transduction and syndromes like cardiofaciocutaneous with features like heart defects and cognitive disability. The anti-MAP2K2 antibody can be used for Western blot (1/1000), Immunocytochemistry (1/50), Immunofluorescence (1/50), Immunohistochemistry-paraffin (1/200).
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51993/if_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51993/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3835/640_C4_2_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3835/640_C4_2_selected.jpg
Figure 3 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51993/ihc_selected.jpg
(Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/51993/ihc_selected.jpg
Figure 4 IHC staining of human stomach
(Immunohistochemical staining of human stomach shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3835/ihc_selected.jpg
(Immunohistochemical staining of human stomach shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3835/ihc_selected.jpg
Figure 5 Skin
(Epidermal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3835/11077_B_4_8.jpg
(Epidermal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3835/11077_B_4_8.jpg
Figure 6 Lymph node
(Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3835/11077_A_7_8.jpg
(Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3835/11077_A_7_8.jpg
Figure 7 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3835/11077_A_7_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3835/11077_A_7_4.jpg
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000126934-MAP2K2
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000126934-MAP2K2
Specifications
- Immunogen
- Recombinant human MEK1, aa 1-393.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat MAP2K2
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC, IF, IHC-P, IP
- Conjugate
- NONE
- Related Disease
- cardiofaciocutaneous syndrome (CFC syndrome)
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/1000
Immunocytochemistry (ICC): 1/50
Immunofluorescence (IF): 1/50
Immunohistochemistry-paraffin (IHC-P): 1/200
Target
- Alternative Names
- Mitogen-Activated Protein Kinase Kinase 2; ERK Activator Kinase 2; MAP Kinase Kinase 2; MAPK/ERK Kinase 2; EC 2.7.12.2; PRKMK2; MEK2; MKK2;
- Gene ID
- 5605
- UniProt ID
- P36507
- Long Name
- Mitogen-Activated Protein Kinase Kinase 2
- Sequence Similarities
- Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
- Cellular Localization
- Nucleus; Cytoplasm; Mitochondrion; Cell membrane
- Protein Refseq
- XP_006722862.1; XP_047295056.1; XP_054177439.1; XP_054177440.1; NP_109587.1
- Function
- Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MAP2K2"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibodies
Rabbit Monoclonal Antibodies
Antibody Magnetic Beads
IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1130CT | Recombinant Mouse anti-Human MAP2K2 Monoclonal antibody (2B2) | IP, WB | |
| MOB-0103F | Mouse Anti-MAP2K2 Recombinant Antibody (clone 2C3) | WB | Mouse IgG |
| MOB-0104F | Mouse Anti-MAP2K2 Recombinant Antibody (clone 7D11) | WB | Mouse IgG |
| VS3-CJ915 | Mouse Anti-MAP2K2 Recombinant Antibody (VS3-CJ915) | WB | Mouse IgG |
| VS3-CJ916 | Rabbit Anti-MAP2K2 Recombinant Antibody (VS3-CJ916) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS13-YC688. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, WB
Application: ELISA, Neut, IF, IP, FC, FuncS
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, IHC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: WB, ELISA, FuncS
Application: ELISA, Inhib, FuncS
Application: WB, ELISA, IHC, IP, SPR, FuncS
-4.jpg)
Application: FC, FuncS, IA, IF, IP, IHC
Application: Neut, IHC, Activ, FuncS, IF, ELISA
For Research Use Only. Not For Clinical Use.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
