AbPlus™ Anti-MBD4 Magnetic Beads (VS-0724-YC156) (CAT#: VS-0724-YC156)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-MBD4 specific antibody

• Target
• MBD4

• Immunogen
• Synthetic peptide corresponding to the center region of the human MBD4.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]

• Alternative Names
• Methyl-CpG Binding Domain 4, DNA Glycosylase; Methyl-CpG Binding Domain Protein 4; Mismatch-Specific DNA N-Glycosylase; Methyl-CpG-Binding Endonuclease 1; Methyl-CpG-Binding Protein MBD4; MED1; G/5-Fluorouracil Mismatch Glycosylase With Biphasic Kinetics;

• Gene ID
• 8930

• UniProt ID
• O95243

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