AbPlus™ Anti-MFN2 Magnetic Beads (VS-0724-YC638)
CAT#: VS-0724-YC638
The AbPlus Anti-MFN2 Magnetic Beads (VS-0724-YC638) is an innovative affinity resin which is bound with anti-MFN2 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of MFN2 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/79902/1987_B9_6_selected.jpg
Normal Tissue
Figure 2 IHC staining of human heart muscle
Immunohistochemical staining of human heart muscle shows moderate cytoplasmic positivity in myocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30554/66797_B_4_6_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30554/66797_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30554/66797_A_8_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30554/66797_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30554/66797_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/30554/66797_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000116688-MFN2
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-MFN2 specific antibody
- Target
- MFN2
- Immunogen
- Recombinant human MFN2 fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
- Alternative Names
- Mitofusin 2; Transmembrane GTPase MFN2; CPRP1; Mitochondrial Assembly Regulatory Factor; Hyperplasia Suppressor; Mitofusin-2; EC 3.6.5.-; KIAA0214; EC 3.6.5;
- Gene ID
- 9927
- UniProt ID
- O95140
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MFN2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2223 | Hi-Affi™ Recombinant Rabbit Anti-MFN2 Monoclonal Antibody (DS2223AB) | WB, IHC, ICC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2034-CN | Rabbit Anti-MFN2 Polyclonal Antibody (MRO-2034-CN) | WB, IF, FC | Rabbit IgG |
| ZG-0080U | Rabbit Anti-MFN2 Recombinant Antibody (clone 10F6) | ELISA, IHC | Rabbit IgG |
| VS-0422-LC146 | Mouse Anti-Mfn2 Recombinant Antibody (clone mN153/5.1) | ICC, WB, IF | Mouse IgG2a |
| VS-0422-LC147 | Rabbit Anti-Mfn2 Recombinant Antibody (clone rN153/5.1) | ICC, WB, IF | Rabbit IgG |
| VS3-FY2117 | Rabbit Anti-MFN2 Recombinant Antibody (clone R56-8V-9) | WB, IHC-P, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1344 | Anti-MFN2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4374 | Anti-Mouse MFN2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4373 | Anti-Human MFN2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4375 | Anti-Rat MFN2 Immunohistochemistry Kit | IHC |
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