Mouse Anti-MICB Recombinant Antibody (clone 1B2F11) (CAT#: VS7-0425-WR384)
This product is a mouse IgG1 antibody that binds to human MICB. The antibody 1B2F11 recognizes specific amino acid domain of human MICB (AA: extra 23-309). It can be used for FC assay.
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm, plasma membrane & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64618/1446_E9_5_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm, plasma membrane & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64618/1446_E9_5_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204516-MICB
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000204516-MICB
Specifications
- Immunogen
- Recombinant human MICB (AA: extra 23-309) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human MICB
- Species Reactivity
- Human
- Clone
- 1B2F11
- Molecule Class
- Non-Classical Mhc Class I-Related Molecule
- Applications
- FC
- Conjugate
- Unconjugated
- Related Disease
- Rheumatoid arthritis (RA)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- MICB; MIC-B; MHC Class I-Like Molecule PERB11.2-IMX; MHC Class I Chain-Related Protein B; PERB11.2; Stress Inducible Class I Homolog; MHC Class I Mic-B Antigen; MHC Class I Polypeptide-Related Sequence B
- Gene ID
- 4277
- UniProt ID
- Q29980
- Long Name
- MHC Class I Polypeptide-Related Sequence B
- Cellular Localization
- Cell membrane; Membrane
- Post Translation Modifications
- Disulfide bond; Glycoprotein
- Protein Refseq
- NP_001276089.1
- Function
- Widely expressed membrane-bound protein which acts as a ligand to stimulate an activating receptor KLRK1/NKG2D, expressed on the surface of essentially all human natural killer (NK), gammadelta T and CD8+ alphabeta T-cells (PubMed:11491531, PubMed:11777960).; Up-regulated in stressed conditions, such as viral and bacterial infections or DNA damage response, serves as signal of cellular stress, and engagement of KLRK1/NKG2D by MICA triggers NK-cells resulting in a range of immune effector functions, such as cytotoxicity and cytokine production
Recommended Products
Isotype Control
Secondary Antibody
Reconstitution Buffer
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3208z | Mouse Anti-MICB Recombinant Antibody (clone 25D2) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| MOB-1235CT | Recombinant Mouse anti-Human MICB Monoclonal antibody (NN0584-4D48) | FC, WB | |
| HPAB-N0178-YC | Mouse Anti-MICB Recombinant Antibody (HPAB-N0178-YC) | ELISA, FC | Mouse IgG2 |
| VS-0723-WK236 | Rabbit Anti-MICB Recombinant Antibody (VS-0723-WK236) | ELISA, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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