Rabbit Anti-NDUFAF4 Recombinant Antibody (clone R04-6A6) (CAT#: VS3-FY1788)

• Immunogen
• Recombinant human NDUFAF4 protein

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human NDUFAF4

• Species Reactivity
• Human

• Clone
• R04-6A6

• Applications
• Western Blot, Immunofluorescence, Immunoprecipitation

• MW
• The calculated weight of the target protein is approximately 20 kDa, while the observed molecular weight stands at 20 kDa.

• Related Disease
• Mitochondrial Complex I Deficiency, Nuclear Type 15 and Mitochondrial Complex I Deficiency, Nuclear Type 1

• Purification
• Affinity Purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000
  Immunofluorescence: 1/50-1/200
  Immunoprecipitation: 1/20

• Alternative Names
• NADH:Ubiquinone Oxidoreductase Complex Assembly Factor 4; NADH Dehydrogenase (Ubiquinone) 1 Alpha Subcomplex, Assembly Factor 4; NADH Dehydrogenase (Ubiquinone) Complex I, Assembly Factor 4; Hormone-Regulated Proliferation-Associated Protein Of 20 KDa; C6orf66; HRPAP20; NADH Dehydrogenase [Ubiquinone] 1 Alpha Subcomplex Assembly Factor 4

• Gene ID
• 29078

• UniProt ID
• Q9P032

• Sequence Similarities
• Belongs to the NDUFAF4 family.

• Cellular Localization
• Membrane, Mitochondrion

• Post Translation Modifications
• Phosphorylated on serine.
  Prolactin stimulate serine phosphorylation ().
  (Q9P032-NDUF4_HUMAN)
  Ubiquitination at Lys51, Lys60, Lys66, Lys91, Lys97, and Lys107 (NX_Q9P032 [NX_Q9P032-1])
  Modification sites at PhosphoSitePlus (Q9P032)
  Glycosylation from GlyGen (Q9P032) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• NP_054884.1

• Function
• Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
  May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-054CQ
• Goat Anti-Rabbit IgG Antibody, R-PE

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-055CQ
• Chicken Anti-Rabbit IgG (H&L) Antibody

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