Rabbit Anti-NFKBIB Recombinant Antibody (VS13-YC802)
CAT#: VS13-YC802
The Rabbit Anti-NFKBIB Recombinant Antibody is specific for human and mouse NFKBIB. NFKBIB also encodes an NF-kappa-B inhibitor, trapping NF-kappa-B in the cytoplasm. Phosphorylation leads to its degradation, freeing NF-kappa-B for nuclear translocation and activation. Splice variants provide functional diversity. The anti-NFKBIB antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100), Immunoprecipitation (1/20).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A549
Immunofluorescent staining of human cell line A549 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63734/1139_C10_2_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000104825-NFKBIB
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Specifications
- Immunogen
- Recombinant human IKB beta.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human and Mouse NFKBIB
- Species Reactivity
- Human, Mouse
- Applications
- WB, IHC-P, IP
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Immunoprecipitation (IP): 1/20
Target
- Alternative Names
- NFKB Inhibitor Beta; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells Inhibitor, Beta; Thyroid Receptor-Interacting Protein 9; NF-Kappa-B Inhibitor Beta; TR-Interacting Protein 9; I-Kappa-B-Beta; NF-Kappa-BIB;
- Gene ID
- 4793
- UniProt ID
- Q15653
- Long Name
- NFKB Inhibitor Beta
- Sequence Similarities
- Belongs to the NF-kappa-B inhibitor family.
- Cellular Localization
- Cytoplasm; Nucleus
- Protein Refseq
- NP_001230045.1; NP_002494.2
- Function
- Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "NFKBIB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-485MZ | Human Anti-NFKBIB Recombinant Antibody (TAB-485MZ) | Cyt, FC, WB | Human IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-485MZ-S(P) | Human Anti-NFKBIB Recombinant Antibody; scFv Fragment (TAB-485MZ-S(P)) | FC, Confocal microscopy, WB, IP | Human scFv |
| TAB-485MZ-F(E) | Human Anti-NFKBIB Recombinant Antibody; Fab Fragment (TAB-485MZ-F(E)) | FC, Confocal microscopy, WB, IP | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2436 | Hi-Affi™ Recombinant Rabbit Anti-NFKBIB Monoclonal Antibody (DS2436AB) | ICC, IHC-P, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-QX814 | Mouse Anti-NFKBIB Recombinant Antibody (clone 3H3-6E9-9H9) | IHC | Mouse IgG1 |
| VS3-QX815 | Mouse Anti-NFKBIB Recombinant Antibody (clone 5H3-4C7-1H6) | IHC | Mouse IgG1 |
| VS3-QX816 | Mouse Anti-NFKBIB Recombinant Antibody (clone 8D11) | IHC | Mouse IgG1 |
| VS3-QX817 | Mouse Anti-NFKBIB Recombinant Antibody (clone 4B11-E1-B6) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS4-CJ55 | Recombinant Mouse Anti-NFKBIB Antibody (VS4-CJ55) | ELISA, IHC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1227 | AbPlus™ Anti-NFKBIB Magnetic Beads (VS-0724-YC1227) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4823 | Anti-NFKBIB Immunohistochemistry Kit | IHC |
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