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NFKBIB
Anti-NFKBIB Recombinant Antibody Products
- Mouse Anti-NFKBIB Recombinant Antibody (clone 3E4) (VS3-WK1598)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: IHC-P, WB
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- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: IHC-P, IF
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
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- AbPlus™ Anti-NFKBIB Magnetic Beads (VS-0724-YC1227) (VS-0724-YC1227)
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- Target: NFKBIB
- Target Species: Human
- Application: IP, Protein Purification
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- Human Anti-NFKBIB Antibody, mRNA (TAB-685CL-mRNA)
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- Species Reactivity: Human
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Group enriched (Late spermatids, Early spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HDLM-2)
Interaction
Interacts with THRB (via ligand-binding domain) (PubMed:7776974). Interacts with RELA and REL (By similarity). Interacts with COMMD1 (PubMed:16573520). Interacts with inhibitor kappa B-interacting Ras-like NKIRAS1 and NKIRAS2 (PubMed:10657303, PubMed:12672800, PubMed:15024091).
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