Mouse Anti-NHP RYR1 Recombinant Antibody (clone 34C) (CAT#: VS-1024-XY460)
Designed to recognize RYR1, this exceptional monoclonal antibody displays broad reactivity across diverse species, including amphibians, bovines, fish, humans, mustelids, mice, non-human primates, sheep, rabbits, and rats. Utilizing a partially purified chicken pectoral muscle ryanodine receptor as its immunogen, it ensures high specificity and effective binding. Ideal for applications in Western blotting and immunohistochemistry, this antibody is indispensable for investigating RYR1's role in calcium signaling and muscle physiology. Its robustness and versatility make it a valuable resource for researchers delving into the complexities of RYR1 function across various biological contexts.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56416/1183_H4_2_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56416/1183_H4_2_selected.jpg
Figure 2 High expression in skeletal muscle
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56416/140331_B_2_6_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56416/140331_B_2_6_val_selected.jpg
Figure 3 Low expression in colon
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56416/140331_A_8_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56416/140331_A_8_3_val_selected.jpg
Figure 4 Skeletal muscle
(Myocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56416/140331_B_1_6.jpg
(Myocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56416/140331_B_1_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (A549, HaCaT, hTCEpi, RH-30, SiHa, U-2 OS)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196218-RYR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000196218-RYR1
Specifications
- Immunogen
- Partially purified chicken pectoral muscle ryanodine receptor
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- RYR1
- Species Reactivity
- Amphibian, Bovine, Fish, Human, Mustelid, Mouse, Non-human primate, Sheep, Rabbit, Rat
- Clone
- 34C
- Applications
- WB, IHC
Product Property
- Purification
- Protein A purified
- Purity
- >95%, determined by SDS-PAGE
- Format
- Liquid
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- WB: 1:5,000, IHC: 1:20
Target
- Alternative Names
- CCO; KDS; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; CMYO1A; CMYO1B; CMYP1A; CMYP1B; PPP1R137
- Gene ID
- 6261
- UniProt ID
- P21817
Recommended Products
Recommended Dilution Buffer
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Blocking Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1355z | Mouse Anti-RYR1 Recombinant Antibody (clone 41B1) | ELISA, FC, IF, IHC, WB | Mouse IgG2b |
| MRO-2173-CN | Rabbit Anti-RYR1 Polyclonal Antibody (MRO-2173-CN) | Dot, IHC, FC | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
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