Rabbit Anti-NME3 Recombinant Antibody (VS13-YC820) (CAT#: VS13-YC820)
The Rabbit Anti-NME3 Recombinant Antibody is specific for human NME3. NME3 primarily synthesizes nucleoside triphosphates, potentially inhibiting granulocyte differentiation and inducing apoptosis, impacting hematopoietic function. The anti-NME3 antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100), Immunoprecipitation (1/20).
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Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52733/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52733/if_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (HEK93)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000103024-NME3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000103024-NME3
Specifications
- Immunogen
- Recombinant human NME3.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human NME3
- Species Reactivity
- Human
- Applications
- WB, IHC-P, IP
- Conjugate
- NONE
- Related Disease
- Breast cancer
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Immunoprecipitation (IP): 1/20
Target
- Alternative Names
- NME/NM23 Nucleoside Diphosphate Kinase 3; Non-Metastatic Cells 3, Protein Expressed In; Nucleoside Diphosphate Kinase C; NDP Kinase 3; EC 2.7.4.6; NM23-H3; DR-Nm23; NDK 3;
- Gene ID
- 4832
- UniProt ID
- Q13232
- Long Name
- NME/NM23 Nucleoside Diphosphate Kinase 3
- Sequence Similarities
- Belongs to the NDK family.
- Cellular Localization
- Cell projection; Cytoplasm; Cytoskeleton; Membrane; Mitochondrion; Mitochondrion outer membrane
- Protein Refseq
- XP_005255389.1; XP_011520805.1; XP_011520806.1; XP_054236378.1; XP_054236379.1
- Function
- The ATP gamma phosphate is transferred to the nucleoside diphosphate beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Through the catalyzed exchange of gamma-phosphate between di- and triphosphonucleosides participates in regulation of intracellular nucleotide homeostasis.
Inhibits granulocyte differentiation.
May be required for ciliary function during renal development (By similarity).
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody Products
IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2458 | Hi-Affi™ Recombinant Rabbit Anti-NME3 Monoclonal Antibody (DS2458AB) | WB, IHC-P, FC, IP | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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