Rabbit Anti-NOP10 Recombinant Antibody (clone R05-5C3)
CAT#: VS3-FY2052
Immunohistochemistry analysis of paraffin-embedded human tonsil using this rabbit recombinant monoclonal antibody, it demonstrates binding to human NOP10. It is suitable for use in a variety of assays, including WB, IHC-P.
Tested Data
IHC
Figure 2 Anti-NOP10 Antibody (VS3-FY2052) in IHC.
Immunohistochemistry staining of paraffin-embedded human tonsil using the anti-NOP10 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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Specifications
- Immunogen
- Synthetic peptide of human NOP10
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human NOP10
- Species Reactivity
- Human
- Clone
- R05-5C3
- Applications
- Western Blot, Immunohistochemistry-Paraffin
- MW
- The calculated weight of the target protein is approximately 8 kDa, while the observed molecular weight stands at 8 kDa.
- Related Disease
- Dyskeratosis Congenita, Autosomal Recessive 1 and Pulmonary Fibrosis And/Or Bone Marrow Failure Syndrome, Telomere-Related, 9
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunohistochemistry: 1/50-1/100
Target
- Alternative Names
- NOP10 Ribonucleoprotein; Nucleolar Protein Family A, Member 3 (H/ACA Small Nucleolar RNPs); Nucleolar Protein Family A Member 3; Homolog Of Yeast Nop10p; Nucleolar Protein 10; SnoRNP Protein NOP10; NOLA3
- Gene ID
- 55505
- UniProt ID
- Q9NPE3
- Sequence Similarities
- Belongs to the NOP10 family.
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q9NPE3)
Modification sites at neXtProt (NX_Q9NPE3)
Glycosylation from GlyGen (Q9NPE3) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_061118.1
- Function
- Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA.
This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "NOP10"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC825 | Rabbit Anti-NOP10 Recombinant Antibody (VS13-YC825) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4896 | Anti-NOP10 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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