AbPlus™ Anti-NR3C2 Magnetic Beads (VS-0724-YC351) (CAT#: VS-0724-YC351)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-NR3C2 specific antibody

• Target
• NR3C2

• Immunogen
• Synthetic peptide corresponding to the C-terminus of the human NR3C2.

• Target Species
• Human, Mouse, Rat

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

• Alternative Names
• Nuclear Receptor Subfamily 3 Group C Member 2; MLR; MCR; MR; Nuclear Receptor Subfamily 3, Group C, Member 2 Variant 3; Nuclear Receptor Subfamily 3, Group C, Member 2; Mineralocorticoid Receptor Delta;

• Gene ID
• 4306

• UniProt ID
• P08235

Select a product category from the dropdown menu below to view related products.