AbPlus™ Anti-OGT Magnetic Beads (VS-0724-YC329) (CAT#: VS-0724-YC329)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-OGT specific antibody

• Target
• OGT

• Immunogen
• Synthetic peptide corresponding to the center region of the human OGT/O-Linked N-Acetylglucosamine Transferase.

• Target Species
• Human, Mouse, Rat

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

• Alternative Names
• O-Linked N-Acetylglucosamine (GlcNAc) Transferase; O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:Polypeptide-N-Acetylglucosaminyl Transferase); UDP-N-Acetylglucosamine:Polypeptide-N-Acetylglucosaminyl Transferase; O-Linked N-Acetylglucosamine Transferase 110 KDa Subunit; O-GlcNAc Transferase Subunit P110; Uridinediphospho-N-Acetylglucosamine:Polypeptide Beta-N-Acetylglucosaminyl Transferase; UDP-N-Acetylglucosamine--Peptide N-Acetylglucosaminyltransferase 110 KDa Subunit; O-GlcNAc Transferase P110 Subunit; EC 2.4.1.186;

• Gene ID
• 8473

• UniProt ID
• O15294

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