Rabbit Anti-OSBPL1A Recombinant Antibody (clone R02-2E2) (CAT#: VS3-FY1809)
This R02-2E2 recombinant monoclonal antibody is specifically directed against human OSBPL1A. It cross-reacts with mouse, rat. It is suitable for use in a variety of assays, including WB, ICC/IF, IP. This ORP1 antibody was used in western blot analysis of ORP1 in rat brain, C6, Hela lysates.
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WB
Figure 1 Anti-OSBPL1A Antibody (VS3-FY1809) in WB.
The ORP1 expression in rat Brain, C6, Hela lysates were detected using the anti-ORP1 by western blot assay.
Specifications
- Immunogen
- Synthetic peptide of human ORP1
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat OSBPL1A
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R02-2E2
- Applications
- Western Blot, Immunofluorescence, Immunoprecipitation
- MW
- The calculated weight of the target protein is approximately 108 kDa, while the observed molecular weight stands at 109,50 kDa.
Product Property
- Purification
- Affinity Purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunofluorescence: 1/50-1/200
Immunoprecipitation: 1/20
Target
- Alternative Names
- Oxysterol Binding Protein Like 1A; Oxysterol Binding Protein-Like 1B; OSBP-Related Protein 1; OSBPL1B; ORP-1; ORP1; Oxysterol-Binding Protein-Related Protein 1 Variant 1
- Gene ID
- 114876
- UniProt ID
- Q9BXW6
- Sequence Similarities
- Belongs to the OSBP family.
- Cellular Localization
- Endosome
- Post Translation Modifications
- Modification sites at PhosphoSitePlus (Q9BXW6)
Modification sites at neXtProt (NX_Q9BXW6)
Glycosylation from GlyGen (Q9BXW6) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- XP_016881019.1; XP_047293243.1; XP_054174146.1; XP_054174147.1; NP_001229437.1
- Function
- Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity).
Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A.
Binds 25-hydroxycholesterol and cholesterol.
Recommended Products
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2555 | Hi-Affi™ Recombinant Rabbit Anti-OSBPL1A Monoclonal Antibody (DS2555AB) | WB, IP, FC | IgG |
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