Rabbit Anti-PARK7 Recombinant Antibody (VS13-YC867)
CAT#: VS13-YC867
The Rabbit Anti-PARK7 Recombinant Antibody is specific for human, mouse and rat PARK7. PARK7 encodes a chaperone and redox sensor protecting neurons from oxidative stress, with mutations causing early-onset Parkinson's disease, exhibiting transcript variants. The anti-PARK7 antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100), Immunofluorescence (1/50-1/200), Immunoprecipitation (1/20).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4190/63_B12_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human pancreas
Immunohistochemical staining of human pancreas shows cytoplasmic and nuclear positivity in exocrine glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4190/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4190/13269_B_7_5.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4190/13269_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4190/13269_A_7_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Round or early spermatids Staining: Low Intensity: Moderate Quantity: <25% Spermatogonia cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4190/13269_A_6_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4190/13269_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000116288-PARK7
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Specifications
- Immunogen
- Recombinant human PARK7.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat PARK7
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-Fr, IHC-P, ICC, IF, IP
- Conjugate
- NONE
- Related Disease
- Autosomal recessive early-onset Parkinson disease
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Immunofluorescence (IF): 1/50-1/200
Immunoprecipitation (IP): 1/20
Target
- Alternative Names
- Parkinsonism Associated Deglycase; Parkinson Disease (Autosomal Recessive, Early Onset) 7; Parkinson Protein 7; Maillard Deglycase; Oncogene DJ1; Protein DJ-1; DJ-1; Epididymis Secretory Sperm Binding Protein Li 67p; Protein/Nucleic Acid Deglycase DJ-1; Parkinsonism-Associated Deglycase;
- Gene ID
- 11315
- UniProt ID
- Q99497
- Long Name
- Parkinsonism Associated Deglycase
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "PARK7"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1769z | Mouse Anti-PARK7 Recombinant Antibody (clone 3B10) | WB, ELISA, FC, ICC, IF | Mouse IgG2b, κ |
| MOB-1544CT | Recombinant Mouse anti-Human PARK7 Monoclonal antibody (nbmqibEK-2/F3.20) | ICC, IF, IHC-FoFr, IHC-Fr, WB | |
| MRO-1163-CN | Recombinant Rabbit Anti-PARK7 Monoclonal Antibody (CBACN-424) | WB, IF, IHC, IP, FC | Rabbit IgG |
| VS3-WK1113 | Rabbit Anti-PARK7 Recombinant Antibody (VS3-WK1113) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
| VS3-FY1093 | Recombinant Mouse Anti-PARK7 Antibody (clone 2B1D7) | ELISA, WB, IHC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2592 | Hi-Affi™ Recombinant Rabbit Anti-PARK7 Monoclonal Antibody (DS2592AB) | WB, IHC-P, ICC, FC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-1014LC | Recombinant Mouse Anti-PARK7 Antibody (3E8) | WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC932 | AbPlus™ Anti-PARK7 Magnetic Beads (VS-0724-YC932) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1563 | Anti-PARK7 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5181 | Anti-Mouse PARK7 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5180 | Anti-Human PARK7 Immunohistochemistry Kit | IHC |
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