Recombinant Human Anti-PfCSP Antibody (mab311) (CAT#: PABC-511)

This product is a recombinant Human antibody that can recognize PfCSP. The mAb311 epitope was proposed to consist of a minimum of two to three NPNA repeats.

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Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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  • Published Data
  • Datasheet
  • MSDS
  • COA
IF

Figure 1 Human Anti-PfCSP Antibody (mab311) in IF.

Figure 1 Human Anti-PfCSP Antibody (mab311) in IF.

In vivo mice protection studies. Representative mAb immunofluorescence reactivity (green) with Pf sporozoites. Phase-contrast and fluorescence channels are shown.

Pholcharee, T. , Oyen, D. , Torres, J. L. , Flores-Garcia, Y. , & Wilson, I. A. . (2019). Diverse antibody responses to conserved structural motifs in plasmodium falciparum circumsporozoite protein. Journal of Molecular Biology, 432(4).

ELISA

Figure 2 Human Anti-PfCSP Antibody (mab311) in ELISA.

Figure 2 Human Anti-PfCSP Antibody (mab311) in ELISA.

Binding of different concentrations of mAbs to PfSPZ in an ELISA. OD405 nm = optical density at 405 nm. Error bars represent standard deviation (SD; N = 2).

Pholcharee, T. , Oyen, D. , Torres, J. L. , Flores-Garcia, Y. , & Wilson, I. A. . (2019). Diverse antibody responses to conserved structural motifs in plasmodium falciparum circumsporozoite protein. Journal of Molecular Biology, 432(4).


Specifications

  • Immunogen
  • P. berghei chimeric sporozoites expressing P. falciparum CSP (3D7 strain)
  • Host Species
  • Human
  • Type
  • Human IgG1, λ
  • Specificity
  • PfCSP
  • Species Reactivity
  • P. falciparum
  • Clone
  • mab311
  • Applications
  • ELISA, FuncS

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • P. falciparum circumsporozoite protein; PfCSP

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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