Recombinant Human Anti-PfCSP Antibody (mab311) (CAT#: PABC-511)

This product is a recombinant Human antibody that can recognize PfCSP. The mAb311 epitope was proposed to consist of a minimum of two to three NPNA repeats.

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IF

Figure 1 Human Anti-PfCSP Antibody (mab311) in IF.

Figure 1 Human Anti-PfCSP Antibody (mab311) in IF.

In vivo mice protection studies. Representative mAb immunofluorescence reactivity (green) with Pf sporozoites. Phase-contrast and fluorescence channels are shown.

Pholcharee, T. , Oyen, D. , Torres, J. L. , Flores-Garcia, Y. , & Wilson, I. A. . (2019). Diverse antibody responses to conserved structural motifs in plasmodium falciparum circumsporozoite protein. Journal of Molecular Biology, 432(4).

ELISA

Figure 2 Human Anti-PfCSP Antibody (mab311) in ELISA.

Figure 2 Human Anti-PfCSP Antibody (mab311) in ELISA.

Binding of different concentrations of mAbs to PfSPZ in an ELISA. OD405 nm = optical density at 405 nm. Error bars represent standard deviation (SD; N = 2).

Pholcharee, T. , Oyen, D. , Torres, J. L. , Flores-Garcia, Y. , & Wilson, I. A. . (2019). Diverse antibody responses to conserved structural motifs in plasmodium falciparum circumsporozoite protein. Journal of Molecular Biology, 432(4).


Specifications

  • Immunogen
  • P. berghei chimeric sporozoites expressing P. falciparum CSP (3D7 strain)
  • Host Species
  • Human
  • Type
  • Human IgG1, λ
  • Specificity
  • PfCSP
  • Species Reactivity
  • P. falciparum
  • Clone
  • mab311
  • Applications
  • ELISA, FuncS

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • P. falciparum circumsporozoite protein; PfCSP

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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